{"id":3027,"date":"2019-07-10T00:00:00","date_gmt":"2021-03-18T06:24:01","guid":{"rendered":"https:\/\/www.eisai.com.cn\/?p=3027"},"modified":"2021-03-18T14:24:01","modified_gmt":"2021-03-18T06:24:01","slug":"%e4%b8%ba%e4%ba%86%e5%bc%80%e5%b1%95%e5%88%9b%e6%96%b0%e6%80%a7%e7%97%b4%e5%91%86%e7%97%87%e7%96%97%e6%b3%95%e7%9a%84%e6%96%b0%e8%8d%af%e7%a0%94%e5%8f%91-%e5%8d%ab%e6%9d%90%e9%81%97%e4%bc%a0%e5%ad%a6","status":"publish","type":"post","link":"https:\/\/www.eisai.com.cn\/2019\/07\/10\/%e4%b8%ba%e4%ba%86%e5%bc%80%e5%b1%95%e5%88%9b%e6%96%b0%e6%80%a7%e7%97%b4%e5%91%86%e7%97%87%e7%96%97%e6%b3%95%e7%9a%84%e6%96%b0%e8%8d%af%e7%a0%94%e5%8f%91-%e5%8d%ab%e6%9d%90%e9%81%97%e4%bc%a0%e5%ad%a6\/","title":{"rendered":"\u4e3a\u4e86\u5f00\u5c55\u521b\u65b0\u6027\u75f4\u5446\u75c7\u7597\u6cd5\u7684\u65b0\u836f\u7814\u53d1 \u536b\u6750\u9057\u4f20\u5b66\u5bfc\u5411\u75f4\u5446\u75c7\u7814\u7a76\u4e2d\u5fc3\u5ba3\u5e03\u5728\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\u6b63\u5f0f\u6210\u7acb"},"content":{"rendered":"

\u5907\u53d7\u5173\u6ce8\u7684\u96c6\u4eba\u7c7b\u9057\u4f20\u5b66\u3001\u6570\u636e\u79d1\u5b66\u3001\u7cbe\u5bc6\u5316\u5b66\u4e8e\u4e00\u8eab\u7684\u836f\u7269\u7814\u53d1\u9014\u5f84<\/em><\/strong><\/p>\n

\n

\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5176\u4f4d\u4e8e\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\u5168\u65b0\u63a2\u7d22\u6027\u7814\u7a76\u8bbe\u65bd\u2014\u2014\u536b\u6750\u9057\u4f20\u5b66\u5bfc\u5411\u75f4\u5446\u75c7\u7814\u7a76\u4e2d\u5fc3\uff08\u201dEisai Center for Genetics\u00a0 Guided\u00a0 Dementia\u00a0 Discovery\u201d\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201cG2D2\u201d\uff09\u4e3e\u884c\u4e86\u6210\u7acb\u5178\u793c\uff0c\u8be5\u4e2d\u5fc3\u5df2\u5168\u9762\u5f00\u59cb\u76f8\u5173\u7814\u7a76\u6d3b\u52a8\u3002<\/p>\n

\n\"\"\u00a0<\/span>
\n\uff08\u4ece\u5de6\u5230\u53f3\u4e3a\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u53c2\u8bae\u5458Ryan Fattman<\/span>\u3001\u75f4\u5446\u60a3\u8005Mike Belleville<\/span>\u3001\u536b\u6750\u9996\u5e2d\u6267\u884c\u5b98\u5185\u85e4\u6674\u592b\u3001\u54c8\u4f5b\u5927\u5b66\u5316\u5b66\u6559\u6388Yoshito Kishi<\/span>\u3001\u65e5\u672c\u9a7b\u6ce2\u58eb\u987f\u603b\u9886\u4e8b\u9986\u4ee3\u7406\u603b\u9886\u4e8bYasushi Nakamura<\/span>\u3001\u7ecf\u6d4e\u53d1\u5c55\u6267\u884c\u529e\u516c\u5ba4\u4e1a\u52a1\u53d1\u5c55\u526f\u90e8\u957fMark Fuller<\/span>\uff09<\/p>\n

\n

G2D2\u5c06\u536b\u6750\u5728\u4eba\u7c7b\u9057\u4f20\u5b66\u3001\u6570\u636e\u79d1\u5b66\u548c\u7cbe\u5bc6\u5316\u5b66\u4e2d\u57f9\u517b\u51fa\u6765\u7684\u4f18\u52bf\u6574\u5408\u5230\u4e86\u65b0\u836f\u7814\u53d1\u4e2d\uff0c\u4e13\u6ce8\u4e8e\u75f4\u5446\u514d\u75ab\u5b66\u7814\u7a76\uff0c\u610f\u5728\u5c06\u536b\u6750\u7684\u75f4\u5446\u75c7\u7ba1\u7ebf\u6269\u5c55\u5230\u6dc0\u7c89\u6837\u86cb\u767d\uff08A\u03b2\uff09\u548ctau\u4e4b\u5916\u3002\u5177\u4f53\u6765\u8bf4\uff0cG2D2\u5c06\u5229\u7528\u4eba\u7c7b\u9057\u4f20\u5b66\u548c\u4eba\u7c7b\u751f\u7269\u5b66\u6765\u5c1d\u8bd5\u7814\u53d1\u9488\u5bf9\u5927\u8111\u514d\u75ab\u7cfb\u7edf\u7684\u6f5c\u5728\u521b\u65b0\u6027\u75f4\u5446\u75c7\u836f\u7269\u3002<\/p>\n

G2D2\u4f4d\u4e8e\u6c47\u96c6\u4e86\u5b66\u672f\u673a\u6784\u548c\u79c1\u4eba\u7814\u7a76\u673a\u6784\u3001\u4e16\u754c\u9886\u5148\u7684\u751f\u7269\u6280\u672f\u4e2d\u5fc3\u4e4b\u4e00\u7684\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\uff0c\uff0c\u6b63\u5728\u79ef\u6781\u63a8\u8fdb\u4e0e\u4e16\u754c\u4e00\u6d41\u7684\u79d1\u5b66\u673a\u6784\u8fdb\u884c\u5408\u4f5c\u3002\u540c\u65f6\uff0c\u536b\u6750\u795e\u7ecf\u7814\u53d1\u5b75\u5316\u56ed\uff08Eisai Incubator for NeuroDiscovery\uff0ce-IND\uff09\u4e5f\u5229\u7528\u5176\u6240\u5728\u5730\u7684\u4f18\u52bf\uff0c\u4e3a\u4f4d\u4e8e\u5251\u6865\u7684\u521d\u521b\/\u884d\u751f\u516c\u53f8\u63d0\u4f9b\u7a7a\u95f4\uff0c\u8fdb\u884c\u5177\u6709\u6f5c\u5728\u7a81\u7834\u6027\u7684\u7814\u7a76\u3002\u8fd9\u4e9b\u7814\u7a76\u53ef\u80fd\u4f1a\u5bf9\u63a2\u7d22\u7a81\u7834\u6027\u795e\u7ecf\u79d1\u5b66\u7597\u6cd5\u7684\u53d1\u73b0\u4ea7\u751f\u5f71\u54cd\u3002\u6b64\u5916\uff0cG2D2\u8fd8\u8ba1\u5212\u901a\u8fc7\u63d0\u4f9b\u5728\u9057\u4f20\u5b66\u548c\u836f\u7269\u7814\u53d1\u79d1\u5b66\u9886\u57df\u7684\u5b9e\u4e60\u3001\u57f9\u8bad\u9879\u76ee\u548c\u535a\u58eb\u540e\u5956\u5b66\u91d1\uff0c\u4e3a\u57f9\u80b2\u6ce2\u58eb\u987f\u548c\u5251\u6865\u5730\u533a\u7684\u4e0b\u4e00\u4ee3\u79d1\u5b66\u9886\u8896\u505a\u51fa\u8d21\u732e\u3002<\/p>\n

\u968f\u7740G2D2\u7684\u5168\u9762\u8fd0\u4f5c\uff0c\u536b\u6750\u52aa\u529b\u63a2\u7d22\u521b\u65b0\u6027\u7684\u75f4\u5446\u75c7\u6cbb\u7597\u65b9\u6cd5\uff0c\u91c7\u7528\u591a\u7ef4\u5ea6\u3001\u7efc\u5408\u6027\u9014\u5f84\u6765\u6ee1\u8db3\u9700\u6c42\u7f3a\u53e3\uff0c\u4e3a\u6ee1\u8db3\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u7684\u591a\u6837\u5316\u9700\u6c42\uff0c\u5e76\u63d0\u9ad8\u4ed6\u4eec\u7684\u798f\u7949\u800c\u4f5c\u51fa\u52aa\u529b\u3002<\/p>\n

\n

\u5a92\u4f53\u54a8\u8be2\uff1a<\/strong>
\n\u536b\u6750\u682a\u5f0f\u4f1a\u793e
\n\u516c\u5171\u5173\u7cfb\u90e8
\n+ 81-\uff080\uff093-3817-5120<\/p>\n

\n

\u3010\u7f16\u8005\u6309\u3011<\/strong><\/b>
\n1.\u5173\u4e8e\u75f4\u5446\u514d\u75ab<\/strong><\/b>
\n\u7531\u4eba\u7c7b\u9057\u4f20\u5b66\u6240\u652f\u6301\u7684\u836f\u7269\u7814\u53d1\u76ee\u6807\uff0c\u5df2\u88ab\u8bc1\u5b9e\u6bd4\u65e0\u6b64\u652f\u6301\u7684\u7814\u53d1\u76ee\u6807\u6709\u7740\u66f4\u9ad8\u7684\u6210\u529f\u6982\u7387\u3002\u5173\u4e8e\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u5927\u89c4\u6a21\u9057\u4f20\u7814\u7a76\u548c\u5176\u5b83\u7814\u7a76\u90fd\u5f3a\u8c03\u4e86\u7279\u5b9a\u7ec6\u80de\u7c7b\u578b\u7684\u795e\u7ecf\u514d\u75ab\u8c03\u8282\u56e0\u5b50\u2014\u2014\u5c0f\u80f6\u8d28\u7ec6\u80de\uff0c\u8ba4\u4e3a\u5176\u53ef\u80fd\u662f\u75f4\u5446\u53d1\u75c5\u7684\u8bf1\u56e0\u3002G2D2\u878d\u5408\u4e86\u4eba\u7c7b\u9057\u4f20\u5b66\u3001\u6570\u636e\u79d1\u5b66\u548c\u7cbe\u5bc6\u5316\u5b66\u7684\u524d\u6cbf\u4f18\u52bf\uff0c\u4e13\u6ce8\u4e8e\u75f4\u5446\u514d\u75ab\u8fd9\u4e00\u65b0\u7814\u7a76\u4e3b\u9898\u3002\u75f4\u5446\u514d\u75ab\u662f\u4e00\u79cd\u5168\u65b0\u7684\u7ecf\u8fc7\u57fa\u56e0\u9a8c\u8bc1\u7684\u9776\u70b9\u8c03\u8282\u514d\u75ab\u673a\u5236\uff0c\u53ef\u6cbb\u7597\u75f4\u5446\u75c7\u3002\u8fd9\u4e00\u673a\u5236\u5c06\u536b\u6750\u7684\u7814\u53d1\u7ba1\u7ebf\u5ef6\u4f38\u5230\u4e86\u6dc0\u7c89\u6837\u86cb\u767d\u548ctau\u9776\u70b9\u4e4b\u5916\u3002\u6839\u636e\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u7684\u4e2d\u671f\u5546\u4e1a\u8ba1\u5212EWAY2025\uff0c\u75f4\u5446\u514d\u75ab\u662fRicchi\uff08\u4e00\u4e2a\u60a3\u8005\u7684\u771f\u6b63\u9700\u6c42\u5c1a\u672a\u5f97\u5230\u6ee1\u8db3\u4e14\u536b\u6750\u53ef\u4ee5\u6210\u4e3a\u9886\u8dd1\u8005\u7684\u9886\u57df\uff09\u3002<\/p>\n

\n

2.<\/strong>\u536b\u6750\u7684\u75f4\u5446\u75c7\u7814\u7a76\u5021\u8bae<\/strong>
\n\u536b\u6750\u5728\u75f4\u5446\u75c7\u9886\u57df\u6709\u774035\u5e74\u7684\u836f\u7269\u521b\u5236\u7ecf\u9a8c\uff0c\u5f00\u53d1\u4e86Aricept\u00ae\u00a0\u8fd9\u4e00\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u6807\u51c6\u7597\u6cd5\uff0c\u5e76\u53d1\u5c55\u4e86\u4e30\u5bcc\u7684\u7814\u53d1\u7ba1\u7ebf\u3002\u6211\u4eec\u4ee5\u7b51\u6ce2\u7814\u7a76\u5b9e\u9a8c\u5ba4\u4e3a\u4e2d\u5fc3\uff0c\u91c7\u7528\u591a\u7ef4\u5ea6\u3001\u7efc\u5408\u6027\u7684\u65b9\u6cd5\uff0c\u901a\u8fc7\u4ee5\u4e0b\u5168\u7403\u7814\u7a76\u673a\u6784\u5bf9\u75f4\u5446\u75c7\u8fdb\u884c\u75f4\u5446\u6cbb\u7597\u65b9\u9762\u7684\u5168\u7403\u6027\u63a2\u7d22\uff1a<\/p>\n