{"id":3210,"date":"2018-10-18T00:00:00","date_gmt":"2021-03-18T08:13:34","guid":{"rendered":"https:\/\/www.eisai.com.cn\/?p=3210"},"modified":"2021-03-18T16:13:34","modified_gmt":"2021-03-18T08:13:34","slug":"%e5%8d%ab%e6%9d%90%e5%9c%a8%e7%ac%ac11%e5%b1%8a%e9%98%bf%e5%b0%94%e8%8c%a8%e6%b5%b7%e9%bb%98%e7%97%85%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e5%a4%a7%e4%bc%9a%e4%b8%8a%e5%8f%91%e5%b8%83%e5%85%b6%e5%9c%a8","status":"publish","type":"post","link":"https:\/\/www.eisai.com.cn\/2018\/10\/18\/%e5%8d%ab%e6%9d%90%e5%9c%a8%e7%ac%ac11%e5%b1%8a%e9%98%bf%e5%b0%94%e8%8c%a8%e6%b5%b7%e9%bb%98%e7%97%85%e4%b8%b4%e5%ba%8a%e8%af%95%e9%aa%8c%e5%a4%a7%e4%bc%9a%e4%b8%8a%e5%8f%91%e5%b8%83%e5%85%b6%e5%9c%a8\/","title":{"rendered":"\u536b\u6750\u5728\u7b2c11\u5c4a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u5927\u4f1a\u4e0a\u53d1\u5e03\u5176\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\/\u75f4\u5446\u836f\u7269\u7814\u53d1\u9886\u57df\u7684\u6700\u65b0\u6570\u636e"},"content":{"rendered":"

–\u00a0<\/em>\u5728\u4e13\u9898\u7814\u8ba8\u4f1a\u4e0a\u62a5\u544aBAN2401\u7684II\u671f\u7814\u7a76\u7ed3\u679c\u7684\u8865\u5145\u6570\u636e\u00a0–\u00a0<\/em><\/p>\n

<\/em><\/p>\n

10\u670818\u65e5\uff0c\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5728\u7b2c11\u5c4a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\uff08CTAD\uff09\u5927\u4f1a\u4e0a\u53d1\u5e03\u4e94\u4e2a\u53e3\u5934\u62a5\u544a\uff0c\u5305\u62ec\u4e00\u4e2a\u4e13\u9898\u7814\u8ba8\u4f1a\u62a5\u544a\u548c\u4e24\u4e2a\u6d77\u62a5\u62a5\u544a\uff0c\u91cd\u70b9\u5c55\u793a\u5176\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\/\u75f4\u5446\u836f\u7269\u7814\u53d1\u9886\u57df\u7684\u6700\u65b0\u7814\u7a76\u6570\u636e\u3002\u76f8\u5173\u836f\u54c1\u5305\u62ec\uff1a\u6297\u6dc0\u7c89\u6837\u86cb\u767d\u03b2\uff08A\u03b2\uff09\u539f\u7ea4\u7ef4\u6297\u4f53BAN2401\uff0c\u53e3\u670d\u03b2\u5206\u6ccc\u9176\uff08BACE\uff09\u6291\u5236\u5242Elenbecestat\uff0c\u6297-A\u03b2\u6297\u4f53Aducanumab\u548c\u53cc\u91cd\u98df\u6b32\u7d20\u53d7\u4f53\u62ee\u6297\u5242Lemborexant\u3002\u7b2c11\u5c4a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\uff08CTAD\uff09\u5927\u4f1a\u4e8e10\u670824\u65e5\u81f327\u65e5\u5728\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u4e3e\u884c\u3002BAN2401\u3001Elenbecestat\u00a0\u548c\u00a0Aducanumab\u00a0\u7531\u536b\u6750\u548c\u6e24\u5065\u516c\u53f8\uff08\u603b\u90e8\u4f4d\u4e8e\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u6e24\u5065\uff08Biogen\uff09\u201d\uff09\u5171\u540c\u7814\u53d1\u3002<\/p>\n

\u5173\u4e8eBAN2401\u7684\u4e13\u9898\u62a5\u544a\u8fdb\u884c\u4e00\u4e2a\u5c0f\u65f6\uff0c\u5bf9201\u7814\u7a76\u9996\u6b21\u53d1\u5e03\u7684\u7ed3\u679c\u8fdb\u884c\u4e34\u5e8a\u548c\u751f\u7269\u6807\u5fd7\u7269\u65b9\u9762\u7684\u66f4\u65b0\u3002\u8be5\u7814\u7a76\u4e8e2018\u5e747\u6708\u9996\u6b21\u53d1\u5e03\u4e86\u7814\u7a76\u7ed3\u679c\uff0c\u7814\u7a76\u5bf9\u8c61\u4e3a\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff08\u7531\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5f15\u8d77\u7684\u8f7b\u5ea6\u8ba4\u77e5\u969c\u788d\u6216\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u6027\u75f4\u5446\uff09\u60a3\u8005\u3002<\/p>\n

\u5173\u4e8eElenbecestat\u7684\u53e3\u5934\u62a5\u544a\u4e2d\u53d1\u5e03\u7814\u7a76202\u7ed3\u679c\u7684\u8865\u5145\u6570\u636e\u3002\u8be5\u7814\u7a76\u4e8e2018\u5e747\u6708\u9996\u6b21\u53d1\u5e03\u4e86\u7814\u7a76\u7ed3\u679c\uff0c\u7814\u7a76\u5bf9\u8c61\u4e3a\u8f7b\u5ea6\u8ba4\u77e5\u969c\u788d\u548c\u8f7b\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u3002\u76ee\u524d\u6b63\u5728\u5bf9Elenbecestat\u8fdb\u884c\u4e24\u4e2aIII\u671f\u4e34\u5e8a\u7814\u7a76\uff08MISSION AD1\/2\uff09\uff0c\u7814\u7a76\u5bf9\u8c61\u662f\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u3002<\/p>\n

\u540c\u65f6\uff0c\u536b\u6750\u8fd8\u5c06\u53d1\u5e03\u51e0\u4e2a\u6709\u5173Aducanumab\u7684\u5ef6\u671f\u63d0\u4ea4\u6458\u8981\uff0c\u5305\u62ec\u4eceIb\u671f\u7814\u7a76PRIME\u7684\u7d2f\u79ef\u5b89\u5168\u6027\u6570\u636e\u4e2d\u5f97\u51fa\u7684\u5206\u6790\u7ed3\u679c\u3002PRIME\u662f\u4e00\u9879\u957f\u671f\u6269\u5c55\u7814\u7a76\uff0c\u5728\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u4e2d\u8fdb\u884c\uff0c\u7814\u7a76\u7ed3\u679c\u9996\u6b21\u53d1\u5e03\u4e8e2018\u5e748\u6708\u3002\u76ee\u524d\u536b\u6750\u548c\u6e24\u5065\uff08Biogen\uff09\u6b63\u5728\u9488\u5bf9Aducanumab\u8fdb\u884c\u4e24\u4e2aIII\u671f\u4e34\u5e8a\u7814\u7a76\uff08ENGAGE\/EMERGE\uff09\u3002<\/p>\n

\u6b64\u5916\uff0c\u536b\u6750\u8fd8\u5c06\u7387\u5148\u53d1\u5e03\u9996\u4e2a\u9488\u5bf9\u7761\u7720\u00a0–\u00a0\u89c9\u9192\u8c03\u8282\u5242Lemborexant\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\uff08202\u7814\u7a76\uff09\u6570\u636e\u3002\u8be5\u7814\u7a76\u5728\u4f34\u6709\u4e0d\u89c4\u5219\u7761\u7720\u00a0–\u00a0\u89c9\u9192\u8282\u5f8b\u7d0a\u4e71\uff08ISWRD\uff09\u7684\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u4e2d\u8fdb\u884c\u3002Lemborexant\u7531\u536b\u6750\u53d1\u73b0\uff0c\u536b\u6750\u548c\u666e\u675c\u5236\u836f\u516c\u53f8\uff08\u603b\u90e8\u4f4d\u4e8e\u7f8e\u56fd\u5eb7\u6d85\u72c4\u683c\u5dde\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u666e\u675c\u201d\uff09\u81ea2015\u5e748\u6708\u8d77\u8fdb\u884c\u8054\u5408\u5f00\u53d1\u3002<\/p>\n

\u57fa\u4e8e30\u591a\u5e74\u5728\u963f\u5c14\u5179\u6d77\u9ed8\u75c5\/\u75f4\u5446\u9886\u57df\u7684\u836f\u7269\u7814\u53d1\u7ecf\u9a8c\uff0c\u536b\u6750\u529b\u6c42\u901a\u8fc7\u5168\u5c40\u7814\u53d1\u75f4\u5446\u836f\u7269\u6765\u5b9e\u73b0\u4ee5\u9632\u6cbb\u75f4\u5446\u3002\u536b\u6750\u81f4\u529b\u4e8e\u5c3d\u5feb\u7814\u53d1\u51fa\u521b\u65b0\u836f\u7269\uff0c\u4e3a\u89e3\u51b3\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u548c\u63d0\u5347\u60a3\u8005\u53ca\u5176\u5bb6\u5c5e\u7684\u798f\u7949\u505a\u51fa\u8d21\u732e\u3002<\/p>\n

\u00a0<\/span><\/p>\n

\u5c06\u5728CTAD 2018\u4e0a\u53d1\u5e03\u7684\u53e3\u5934\u62a5\u544a\uff1a<\/strong><\/b><\/p>\n\n\n\n\n\n\n\n\n
\u4ea7\u54c1\uff0c\u4f1a\u8bae\u7f16\u53f7<\/strong><\/td>\n\u6d77\u62a5\u6807\u9898\u548c\u9884\u5b9a\u62a5\u544a\u65e5\u671f\uff08\u5f53\u5730\u65f6\u95f4\uff09<\/strong><\/td>\n<\/tr>\n
\nBAN2401<\/p>\n

\u4f1a\u8bae\u7f16\u53f7\uff1a\u4e13\u9898\u7814\u8ba8\u4f1a3<\/td>\n

\u5728\u65e9\u671fAD\u60a3\u8005\u4e2d\u8fdb\u884c\u7684\u7814\u7a76201\u4e2dBAN2401\u4e34\u5e8a\u548c\u751f\u7269\u6807\u5fd7\u7269\u66f4\u65b0<\/p>\n

\u4e13\u9898\u7814\u8ba8<\/em><\/strong>\u4f1a| 10\u670825\u65e5\uff08\u661f\u671f\u56db\uff09\uff0c14\uff1a30-15\uff1a30<\/td>\n<\/tr>\n

\nElenbecestat<\/p>\n

\u4f1a\u8bae\u7f16\u53f7\uff1aOC5<\/td>\n

Elenbecestat\u5728\u8f7b\u5ea6\u8ba4\u77e5\u969c\u788d\uff08MCI\uff09\u81f3\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u4e2d\u7684\u5e94\u7528\uff1a\u901a\u8fc7\u6dc0\u7c89\u6837\u86cb\u767dPET\u548cADCOMS\u4e34\u5e8a\u7ec8\u70b9\u6765\u8861\u91cf\u8be5\u836f\u7269\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/p>\n

\u53e3\u5934\u62a5\u544a<\/em><\/strong>| 10\u670825\u65e5\uff08\u661f\u671f\u56db\uff09\uff0c\u00a009:30-09:45<\/td>\n<\/tr>\n

Aducanumab<\/p>\n

\u4f1a\u8bae\u7f16\u53f7\uff1a\u4e3b\u9898\u6f14\u8bb22<\/td>\n

\u6211\u4eec\u4eceAducanumab\u8eab\u4e0a\u5b66\u5230\u4e86\u4ec0\u4e48\uff1f<\/p>\n

\u53e3\u5934\u62a5\u544a<\/em><\/strong>| 10\u670825\u65e5\uff08\u661f\u671f\u56db\uff09\uff0c13:30-14:00<\/td>\n<\/tr>\n

\nAducanumab<\/p>\n

\u4f1a\u8bae\u7f16\u53f7\uff1aLB8<\/td>\n

Aducanumab\u6ef4\u5b9a\u5242\u91cf\u7ed9\u836f\u65b9\u6848\uff1a\u6765\u81ea\u5728\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u4e2d\u8fdb\u884c\u7684PRIME1B\u671f\u7814\u7a76\u768436\u4e2a\u6708\u7684\u5206\u6790<\/p>\n

\u53e3\u5934\u62a5\u544a<\/em><\/strong>| 10\u670826\u65e5\uff08\u661f\u671f\u4e94\uff09\uff0c15:15-15:30<\/td>\n<\/tr>\n

\nLemborexant<\/p>\n

\u4f1a\u8bae\u7f16\u53f7\uff1aOC11<\/td>\n

Lemborexant\u7528\u4e8e\u5bf9\u4e0d\u89c4\u5219\u6027\u7761\u7720\u00a0–\u00a0\u89c9\u9192\u8282\u5f8b\u969c\u788d\u548c\u963f\u5c14\u8328\u6d77\u9ed8\u6027\u75f4\u5446\u60a3\u8005\u8fdb\u884c\u7761\u7720\u00a0–\u00a0\u89c9\u9192\u8c03\u8282\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/p>\n

\u53e3\u5934\u62a5\u544a<\/em><\/strong>| 10\u670825\u65e5\uff08\u661f\u671f\u56db\uff09\uff0c15:30-15:45<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\nCTAD 2018<\/strong><\/b>\u7684\u6d77\u62a5\u62a5\u544a\uff1a<\/strong><\/b><\/p>\n\n\n\n\n\n
\u4ea7\u54c1\uff0c\u6d77\u62a5\u7f16\u53f7<\/strong><\/td>\n\u6d77\u62a5\u6807\u9898\u548c\u9884\u5b9a\u62a5\u544a\u65e5\u671f\uff08\u5f53\u5730\u65f6\u95f4\uff09<\/strong><\/td>\n<\/tr>\n
\nAducanumab<\/p>\n

\u6d77\u62a5\u7f16\u53f7\uff1aP80<\/td>\n

PRIME\u4e2d\u7684Aducanumab\u5b89\u5168\u6027\u6570\u636e\u7d2f\u79ef\uff1a\u4e00\u9879\u968f\u673a\u3001\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u30011b\u671f\u7814\u7a76<\/p>\n

\u6d77\u62a5\u5c55\u793a<\/em><\/strong>| 10\u670824\u65e5\uff08\u5468\u4e09\uff09\u81f310\u670827\u65e5\uff08\u5468\u516d\uff09<\/td>\n<\/tr>\n

\nAducanumab<\/p>\n

\u6d77\u62a5\u7f16\u53f7\uff1aLBP19<\/td>\n

\u5728\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u4e2d\u8fdb\u884c\u7684PRIME1b\u671f\u7814\u7a76\u4e2d\u5173\u4e8eAducanumab\u768448\u4e2a\u6708\u7684\u5206\u6790<\/p>\n

\u6d77\u62a5\u5c55\u793a<\/em><\/strong>| 10\u670824\u65e5\uff08\u5468\u4e09\uff09\u81f310\u670827\u65e5\uff08\u5468\u516d\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\n

\u5a92\u4f53\u54a8\u8be2\uff1a<\/strong><\/b>
\n\u536b\u6750\u682a\u5f0f\u4f1a\u793e
\n\u516c\u5173\u90e8
\n+81-(0)3-3817-5120<\/p>\n

\n

\u3010\u7f16\u8005\u6309\u3011<\/strong><\/b>
\n1.\u00a0\u5173\u4e8eBAN2401
\n<\/strong>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0BAN2401\u662f\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u662f\u536b\u6750\u4e0eBioArctic\u6218\u7565\u7814\u7a76\u8054\u76df\u7684\u7814\u7a76\u6210\u679c\u3002BAN2401\u901a\u8fc7\u9009\u62e9\u6027\u7ed3\u5408\u6765\u4e2d\u548c\u5e76\u6d88\u9664\u53c2\u4e0e\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u795e\u7ecf\u9000\u884c\u6027\u53d8\u5316\u8fc7\u7a0b\u7684\u53ef\u6eb6\u6027\u6bd2\u6027A\u03b2\u805a\u96c6\u4f53\u3002\u56e0\u6b64\uff0cBAN2401\u53ef\u80fd\u4f1a\u5bf9\u75be\u75c5\u75c5\u7406\u4ea7\u751f\u4f5c\u7528\u5e76\u51cf\u7f13\u75be\u75c5\u8fdb\u5c55\u3002\u6839\u636e\u536b\u6750\u4e0eBioArctic\u4e8e2007\u5e7412\u6708\u8fbe\u6210\u7684\u534f\u8bae\uff0c\u536b\u6750\u83b7\u5f97\u5728\u5168\u7403\u7814\u7a76\u3001\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u9500\u552e\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u836f\u7269\u00a0BAN2401\u7684\u6743\u5229\u3002<\/p>\n

2.\u00a0<\/strong>\u5173\u4e8e\u00a0Elenbecestat\uff08\u901a\u7528\u540d\uff0c\u5f00\u53d1\u4ee3\u7801\uff1aE2609\uff09
\n<\/strong>Elenbecestat\u662f\u4e00\u79cd\u53e3\u670d\u00a0BACE\uff08\u03b2\u6dc0\u7c89\u6837\u86cb\u767d\u88c2\u89e3\u9176\uff09\u6291\u5236\u5242\uff0c\u7531\u536b\u6750\u53d1\u73b0\u53ef\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff0c\u76ee\u524d\u5904\u4e8eIII\u671f\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\u3002\u901a\u8fc7\u6291\u5236\u00a0BACE\u8fd9\u4e00\u4ea7\u751fA\u03b2\u80bd\u7684\u5173\u952e\u9176\uff0cElenbecestat\u53ef\u51cf\u5c11A\u03b2\u7684\u4ea7\u751f\uff0c\u4ece\u800c\u51cf\u5c11\u7531\u4e8e\u6bd2\u6027\u5be1\u805a\u7269\u548c\u539f\u7ea4\u7ef4\u5728\u5927\u8111\u4e2d\u805a\u96c6\u800c\u5bfc\u81f4\u7684\u6dc0\u7c89\u6837\u6591\u5757\u7684\u5f62\u6210\u3002\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u4e24\u4e2a\u5173\u4e8eElenbecestat\u7528\u4e8e\u6cbb\u7597\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u5168\u7403III\u671f\u4e34\u5e8a\u7814\u7a76\uff08MISSION AD1\/2\uff09\u3002\u6b64\u5904\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5305\u62ec\u7531\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5f15\u8d77\u7684\u8f7b\u5ea6\u8ba4\u77e5\u635f\u5bb3\uff08MCI\uff09\/\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u524d\u9a71\u671f\u53ca\u8f7b\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u65e9\u671f\u9636\u6bb5\u3002\u6b64\u5916\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u5bf9Elenbecestat\u7684\u7814\u53d1\u6388\u4e88\u4e86\u5feb\u901f\u901a\u9053\u8d44\u683c\u3002FDA\u53ea\u5bf9\u5176\u8ba4\u4e3a\u5177\u6709\u6cbb\u7597\u4e25\u91cd\u75be\u75c5\u548c\u89e3\u51b3\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u6f5c\u529b\u7684\u836f\u7269\u6388\u4e88\u4fc3\u8fdb\u7814\u53d1\u548c\u52a0\u901f\u5ba1\u8bc4\u7684\u901a\u9053\u3002
\n
\n3.\u00a0\u5173\u4e8eAducanumab\uff08BIIB037\uff09
\n<\/strong><\/b>Aducanumab\u662f\u4e00\u79cd\u5c1a\u5728\u7814\u7a76\u9636\u6bb5\u7684\u3001\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u5316\u5408\u836f\u54c1\uff0c\u662f\u901a\u8fc7\u53cd\u5411\u8f6c\u5316\u533b\u5b66\uff08RTM\uff09\u8fd9\u4e00\u795e\u7ecf\u514d\u75ab\u6280\u672f\u5e73\u53f0\u83b7\u5f97\uff0c\u4ece\u65e0\u8ba4\u77e5\u969c\u788d\u5065\u5eb7\u8001\u5e74\u53d7\u8bd5\u8005\u548c\u5177\u6709\u5f02\u5e38\u7f13\u6162\u8ba4\u77e5\u8870\u9000\u7684\u969c\u788d\u6027\u8001\u5e74\u53d7\u8bd5\u8005\u7684\u53bb\u8bc6\u522b\u5316B\u7ec6\u80de\u5e93\u4e2d\u53d1\u73b0\u7684\u4e00\u79cd\u4eba\u6e90\u91cd\u7ec4\u5355\u514b\u9686\u6297\u4f53\uff08mAb\uff09\u3002\u6309\u7167\u6e24\u5065\uff08Biogen\uff09\u548cNeurimmune\u516c\u53f8\u7b7e\u8ba2\u7684\u5408\u4f5c\u5f00\u53d1\u548c\u8bb8\u53ef\u534f\u8bae\uff0c\u6e24\u5065\uff08Biogen\uff09\u4eceNeurimmune\u516c\u53f8\u53d6\u5f97\u4e86Aducanumab\u7684\u7814\u53d1\u548c\u8425\u9500\u6388\u6743\u3002
\nAducanumab\u9776\u5411\u03b2\u6dc0\u7c89\u6837\u86cb\u767d\u7684\u805a\u96c6\u5f62\u5f0f\uff0c\u5305\u62ec\u53ef\u6eb6\u6027\u4f4e\u805a\u7269\u548c\u4e0d\u6eb6\u6027\u7ea4\u7ef4\u3002\u8fd9\u4e24\u79cd\u7269\u8d28\u53ef\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u7684\u5927\u8111\u4e2d\u5f62\u6210\u6dc0\u7c89\u6837\u6591\u5757\u3002\u6839\u636e\u4e34\u5e8a\u524d\u548c1b\u671f\u6570\u636e\uff0c\u7528Aducanumab\u8fdb\u884c\u6cbb\u7597\u53ef\u964d\u4f4e\u6dc0\u7c89\u6837\u6591\u5757\u7684\u6c34\u5e73\u3002
\n2016\u5e748\u6708\uff0cAducanumab\u88ab\u7eb3\u5165\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u7684PRIME\u9879\u76ee\u30022016\u5e749\u6708\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5c06Aducanumab\u7eb3\u5165\u5176\u5feb\u901f\u901a\u9053\u9879\u76ee\u30022017\u5e744\u6708\uff0cAducanumab\u88ab\u7eb3\u5165\u65e5\u672c\u536b\u751f\u52b3\u5de5\u4e0e\u798f\u5229\u90e8\uff08MHLW\uff09\u7684Sakigake\u6307\u5b9a\u7cfb\u7edf\u3002<\/p>\n

4.\u00a0\u5173\u4e8e\u536b\u6750\u548c\u6e24\u5065\uff08Biogen\uff09\u7684\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u836f\u7269\u8054\u5408\u5f00\u53d1\u534f\u8bae<\/strong><\/b>
\n\u536b\u6750\u548c\u6e24\u5065\uff08Biogen\uff09\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u6cbb\u7597\u836f\u7269\u7684\u8054\u5408\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u65b9\u9762\u8fdb\u884c\u7740\u5e7f\u6cdb\u7684\u5408\u4f5c\u3002\u536b\u6750\u5728BACE\u6291\u5236\u5242Elenbecestat\u548c\u6297-A\u03b2\u539f\u7ea4\u7ef4\u6297\u4f53BAN2401\u7684\u5171\u540c\u5f00\u53d1\u65b9\u9762\u5904\u4e8e\u4e3b\u5bfc\u5730\u4f4d\uff0c\u6e24\u5065\uff08Biogen\uff09\u5219\u5728\u9488\u5bf9\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u7684\u5b9e\u9a8c\u6027\u6297-A\u03b2 \u6297\u4f53Aducanumab\u7684\u5171\u540c\u5f00\u53d1\u65b9\u9762\u5904\u4e8e\u4e3b\u5bfc\u5730\u4f4d\uff0c\u4e24\u5bb6\u516c\u53f8\u8ba1\u5212\u5728\u5168\u7403\u83b7\u5f97\u8fd9\u4e09\u79cd\u836f\u7269\u7684\u4e0a\u5e02\u8bb8\u53ef\u3002\u5982\u679c\u83b7\u5f97\u6279\u51c6\uff0c\u4e24\u5bb6\u516c\u53f8\u5c06\u5728\u7f8e\u56fd\u3001\u6b27\u76df\u548c\u65e5\u672c\u7b49\u4e3b\u8981\u5e02\u573a\u5171\u540c\u63a8\u5e7f\u76f8\u5173\u4ea7\u54c1\u3002<\/p>\n

5.\u00a0\u5173\u4e8e\u00a0Lemborexant\u00a0\uff08\u901a\u7528\u540d\uff0c\u5f00\u53d1\u4ee3\u7801\uff1aE2006\uff09<\/strong><\/b>
\nLemborexant\u662f\u4e00\u79cd\u53cc\u98df\u6b32\u7d20\u53d7\u4f53\u62ee\u6297\u5242\uff0c\u7531\u536b\u6750\u5185\u90e8\u53d1\u73b0\u5e76\u7814\u53d1\u3002\u8fd9\u4e00\u5c0f\u5206\u5b50\u5316\u5408\u7269\u901a\u8fc7\u7ade\u4e89\u6027\u5730\u7ed3\u5408\u4e24\u79cd\u4e9a\u578b\u7684\u98df\u6b32\u7d20\u53d7\u4f53\uff08\u98df\u6b32\u7d20\u53d7\u4f531\u548c\u98df\u6b32\u7d20\u53d7\u4f532\uff09\u6765\u6291\u5236\u98df\u6b32\u7d20\u795e\u7ecf\u4f20\u9012\u3002\u60a3\u6709\u7761\u7720\u969c\u788d\u7684\u4eba\u7fa4\u4f53\u5185\u8c03\u8282\u7761\u7720\u548c\u89c9\u9192\u7684\u98df\u6b32\u7d20\u7cfb\u7edf\u65e0\u6cd5\u6b63\u5e38\u8fd0\u8f6c\u3002\u5728\u6b63\u5e38\u7761\u7720\u671f\u95f4\uff0c\u98df\u6b32\u7d20\u7cfb\u7edf\u7684\u6d3b\u8dc3\u5ea6\u88ab\u6291\u5236\uff0c\u6709\u53ef\u80fd\u4f1a\u81ea\u89c9\u963b\u6b62\u4e0d\u6b63\u5e38\u89c9\u9192\uff0c\u5e76\u901a\u8fc7\u5e72\u6270\u98df\u6b32\u7d20\u795e\u7ecf\u4f20\u9012\u6765\u4fc3\u8fdb\u7761\u7720\u5f00\u59cb\u548c\u7ef4\u6301\u7761\u7720\u8fc7\u7a0b\u3002\u56e0\u6b64\uff0c\u536b\u6750\u548c\u666e\u675c\u4e00\u76f4\u5728\u7814\u53d1Lemborexant\u6765\u6cbb\u7597\u591a\u79cd\u7761\u7720\u969c\u788d\u3002
\n\u6b64\u5916\uff0c\u4e00\u9879\u5173\u4e8eLemborexant\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\u6b63\u5728\u4e0d\u89c4\u5219\u7684\u7761\u7720-\u89c9\u9192\u8282\u5f8b\u7d0a\u4e71\uff08ISWRD\uff09\u548c\u8f7b\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75f4\u5446\u60a3\u8005\u4e2d\u8fdb\u884c\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

10\u670818\u65e5\uff0c\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u5ba3\u5e03\uff0c\u8be5\u516c\u53f8\u5728\u7b2c11\u5c4a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\uff08CTAD\uff09\u5927\u4f1a\u4e0a\u53d1\u5e03\u4e94\u4e2a\u53e3\u5934\u62a5\u544a\uff0c\u5305\u62ec\u4e00\u4e2a\u4e13\u9898\u7814\u8ba8\u4f1a\u62a5\u544a\u548c\u4e24\u4e2a\u6d77\u62a5\u62a5\u544a\uff0c\u91cd\u70b9\u5c55\u793a\u5176\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\/\u75f4\u5446\u836f\u7269\u7814\u53d1\u9886\u57df\u7684\u6700\u65b0\u7814\u7a76\u6570\u636e\u3002\u76f8\u5173\u836f\u54c1\u5305\u62ec\uff1a\u6297\u6dc0\u7c89\u6837\u86cb\u767d\u03b2\uff08A\u03b2\uff09\u539f\u7ea4\u7ef4\u6297\u4f53BAN2401\uff0c\u53e3\u670d\u03b2\u5206\u6ccc\u9176\uff08BACE\uff09\u6291\u5236\u5242Elenbecestat\uff0c\u6297-A\u03b2\u6297\u4f53Aducanumab\u548c\u53cc\u91cd\u98df\u6b32\u7d20\u53d7\u4f53\u62ee\u6297\u5242Lemborexant\u3002\u7b2c11\u5c4a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\uff08CTAD\uff09\u5927\u4f1a\u4e8e10\u670824\u65e5\u81f327\u65e5\u5728\u897f\u73ed\u7259\u5df4\u585e\u7f57\u90a3\u4e3e\u884c\u3002BAN2401\u3001Elenbecestat\u00a0\u548c\u00a0Aducanumab\u00a0\u7531\u536b\u6750\u548c\u6e24\u5065\u516c\u53f8\uff08\u603b\u90e8\u4f4d\u4e8e\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u6e24\u5065\uff08Biogen\uff09\u201d\uff09\u5171\u540c\u7814\u53d1\u3002<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-3210","post","type-post","status-publish","format-standard","hentry","category-news-zh"],"_links":{"self":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3210"}],"collection":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/comments?post=3210"}],"version-history":[{"count":2,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3210\/revisions"}],"predecessor-version":[{"id":3217,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3210\/revisions\/3217"}],"wp:attachment":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/media?parent=3210"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/categories?post=3210"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/tags?post=3210"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}