{"id":3224,"date":"2018-10-12T00:00:00","date_gmt":"2021-03-18T08:16:40","guid":{"rendered":"https:\/\/www.eisai.com.cn\/?p=3224"},"modified":"2022-03-11T14:45:14","modified_gmt":"2022-03-11T06:45:14","slug":"%e4%b8%ad%e5%9b%bd%e6%8e%a5%e5%8f%97%e5%90%a1%e4%bb%91%e5%b8%95%e5%a5%88%ef%bc%88perampanel%ef%bc%89%e7%94%a8%e4%ba%8e%e7%99%ab%e7%97%ab%e9%83%a8%e5%88%86%e6%80%a7%e5%8f%91%e4%bd%9c%e5%8a%a0%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.eisai.com.cn\/2018\/10\/12\/%e4%b8%ad%e5%9b%bd%e6%8e%a5%e5%8f%97%e5%90%a1%e4%bb%91%e5%b8%95%e5%a5%88%ef%bc%88perampanel%ef%bc%89%e7%94%a8%e4%ba%8e%e7%99%ab%e7%97%ab%e9%83%a8%e5%88%86%e6%80%a7%e5%8f%91%e4%bd%9c%e5%8a%a0%e7%94%a8\/","title":{"rendered":"\u4e2d\u56fd\u63a5\u53d7\u5421\u4ed1\u5e15\u5948\uff08PERAMPANEL\uff09\u7528\u4e8e\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u52a0\u7528\u6cbb\u7597\u7684\u65b0\u836f\u7533\u8bf7"},"content":{"rendered":"<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0<span lang=\"EN-US\">\u201c<\/span>\u536b\u6750<span lang=\"EN-US\">\u201d<\/span>\uff09\u5ba3\u5e03\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u63a5\u53d7\u536b\u6750\u4e2d\u56fd\u63d0\u4ea4\u7684\u5c06\u6297\u766b\u75eb\u836f\u7269\u5421\u4ed1\u5e15\u5948\uff08\u901a\u7528\u540d\uff0c\u5546\u54c1\u540d\uff1a<span lang=\"EN-US\">Fycompa<\/span>\uff09\u7528\u4e8e\u52a0\u7528\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u766b\u75eb\u60a3\u8005\u7684\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u65b0\u836f\u7533\u8bf7\uff0c\u5e76\u8fdb\u884c\u5ba1\u8bc4\u3002\u8fd9\u662f\u536b\u6750\u7b2c\u4e00\u6b21\u5728\u4e2d\u56fd\u63d0\u4ea4\u5421\u4ed1\u5e15\u5948<span class=\"a0\">\u7684\u65b0\u836f\u7533\u8bf7\u3002 <\/span><\/p>\n<p>\u5421\u4ed1\u5e15\u5948\u7528\u4e8e\u6cbb\u7597\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u65b0\u836f\u7533\u8bf7\u57fa\u4e8e\u4e09\u9879\u4e3b\u8981\u5728\u6b27\u6d32\u548c\u7f8e\u56fd\u5f00\u5c55\u7684<span lang=\"EN-US\">III<\/span>\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u4ee5\u53ca\u4e00\u9879\u4e3b\u8981\u5728\u4e9a\u6d32\u56fd\u5bb6\uff08\u5305\u62ec\u4e2d\u56fd\u548c\u65e5\u672c\uff09\u5f00\u5c55\u7684<span lang=\"EN-US\">III<\/span>\u671f\u4e34\u5e8a\u7814\u7a76\uff08<span lang=\"EN-US\">335<\/span>\u7814\u7a76\uff09\u7684\u7ed3\u679c\u3002<\/p>\n<p>\u4e2d\u56fd\u5927\u7ea6\u6709<span lang=\"EN-US\">900<\/span>\u4e07\u766b\u75eb\u60a3\u8005\uff0c\u5176\u4e2d\u7ea6<span lang=\"EN-US\">60%<\/span>\u4e3a\u90e8\u5206\u6027\u53d1\u4f5c\uff0c\u800c\u90e8\u5206\u6027\u53d1\u4f5c\u60a3\u8005\u4e2d\u53c8\u6709<span lang=\"EN-US\">40%<\/span>\u9700\u8981\u52a0\u7528\u6cbb\u7597\u3002\u5927\u7ea6<span lang=\"EN-US\">30%<\/span>\u7684\u766b\u75eb\u60a3\u8005\u4f7f\u7528\u73b0\u6709\u7684\u6297\u766b\u75eb\u836f\u7269\u4e0d\u80fd\u63a7\u5236\u75c5\u60c5<sup>1<\/sup>\u3002 \u766b\u75eb\u662f\u4e00\u79cd\u533b\u7597\u9700\u6c42\u4e25\u91cd\u672a\u88ab\u6ee1\u8db3\u7684\u75be\u75c5<sup>2<\/sup><span class=\"a0\">\u3002<\/span><\/p>\n<p>\u5421\u4ed1\u5e15\u5948\u662f\u7531\u536b\u6750\u7b51\u6ce2\u7814\u7a76\u6240\u7814\u53d1\u7684\u4e00\u79cd\u9996\u521b\u6297\u766b\u75eb\u836f\u7269\uff0c\u6bcf\u65e5\u53e3\u670d\u4e00\u6b21\u3002\u8be5\u836f\u662f\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u3001\u975e\u7ade\u4e89\u6027\u7684<span lang=\"EN-US\"> AMPA <\/span>\u578b\u53d7\u4f53\u62ee\u6297\u5242\uff0c\u53ef\u901a\u8fc7\u9776\u5411\u6291\u5236\u7a81\u89e6\u540e\u819c<span lang=\"EN-US\">AMPA<\/span>\u53d7\u4f53\u7684\u8c37\u6c28\u9178\u6d3b\u6027\uff0c\u51cf\u5c11\u4e0e\u766b\u75eb\u53d1\u4f5c\u76f8\u5173\u7684\u795e\u7ecf\u5143\u7684\u8fc7\u5ea6\u5174\u594b\u3002<\/p>\n<p>\u5421\u4ed1\u5e15\u5948\u5df2\u5728\u5168\u7403\u8d85\u8fc7<span lang=\"EN-US\">55<\/span>\u4e2a\u56fd\u5bb6\u83b7\u5f97\u6279\u51c6\uff0c\u7528\u4e8e\u52a0\u7528\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u766b\u75eb\u60a3\u8005\u7684\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\uff08\u4f34\u6216\u4e0d\u4f34\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff09\u3002\u53e6\u5916\uff0c\u5421\u4ed1\u5e15\u5948\u5df2\u5728\u5168\u7403<span lang=\"EN-US\">50<\/span>\u591a\u4e2a\u56fd\u5bb6\u83b7\u5f97\u6279\u51c6\uff0c\u7528\u4e8e\u52a0\u7528\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u7684\u766b\u75eb\u60a3\u8005\u7684\u539f\u53d1\u6027\u5168\u9762\u6027\u5f3a\u76f4\u9635\u631b\u53d1\u4f5c\u3002\u5728\u7f8e\u56fd\uff0c\u5421\u4ed1\u5e15\u5948\u5df2\u83b7\u51c6\u7528\u4e8e<span lang=\"EN-US\">4<\/span>\u5c81\u53ca\u4ee5\u4e0a\u60a3\u8005\u7684\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\uff08\u4f34\u6216\u4e0d\u4f34\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff09\u7684\u5355\u836f\u53ca\u52a0\u7528\u6cbb\u7597\u3002<\/p>\n<p>\u536b\u6750\u5c06\u5305\u62ec\u766b\u75eb\u5728\u5185\u7684\u795e\u7ecf\u79d1\u5b66\u89c6\u4e3a\u91cd\u70b9\u6cbb\u7597\u9886\u57df\uff0c\u5e76\u7aed\u5c3d\u5168\u529b\u5c06\u5421\u4ed1\u5e15\u5948\u5c3d\u5feb\u5e26\u7ed9\u4e2d\u56fd\u60a3\u8005\u3002\u4e3a\u9075\u5faa\u4f7f\u4f17\u591a\u766b\u75eb\u60a3\u8005\u6446\u8131\u766b\u75eb\u53d1\u4f5c\u7684\u70e6\u607c\u8fd9\u4e00\u4f7f\u547d\uff0c\u536b\u6750\u81f4\u529b\u4e8e\u6ee1\u8db3\u766b\u75eb\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u7684\u591a\u6837\u5316\u9700\u6c42\uff0c\u5e76\u63d0\u9ad8\u4ed6\u4eec\u7684\u798f\u7949\u3002<\/p>\n<p><span lang=\"EN-US\">\u00a0<\/span><\/p>\n<p><strong>\u5a92\u4f53\u54a8\u8be2\uff1a<\/strong><\/p>\n<p>\u516c\u5173\u90e8<\/p>\n<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e<\/p>\n<p><span lang=\"EN-US\">+81-(0)3-3817-5120<\/span><\/p>\n<p><span lang=\"EN-US\">\u00a0<\/span><\/p>\n<p><b>\u3010\u7f16\u8005\u6309\u3011<\/b><\/p>\n<p><b><span lang=\"EN-US\">1<\/span>\u3001\u5173\u4e8e\u5421\u4ed1\u5e15\u5948\uff08\u901a\u7528\u540d\uff1a<span lang=\"EN-US\">Perampanel<\/span>\uff0c\u5546\u54c1\u540d\uff1a<span lang=\"EN-US\">Fycompa<\/span>\uff09<\/b><\/p>\n<p>\u5421\u4ed1\u5e15\u5948\u662f\u7531\u536b\u6750\u72ec\u5bb6\u7814\u53d1\u7684\u4e00\u79cd\u9996\u521b\u6297\u766b\u75eb\u836f\u7269\u3002\u766b\u75eb\u53d1\u4f5c\u662f\u7531\u795e\u7ecf\u9012\u8d28\u8c37\u6c28\u9178\u4ecb\u5bfc\u7684\u3002\u8be5\u836f\u662f\u4e00\u79cd\u9ad8\u9009\u62e9\u6027\u3001\u975e\u7ade\u4e89\u6027\u7684<span lang=\"EN-US\">AMPA<\/span>\u578b\u53d7\u4f53\u62ee\u6297\u5242\uff0c\u53ef\u901a\u8fc7\u9776\u5411\u6291\u5236\u7a81\u89e6\u540e\u819c<span lang=\"EN-US\">AMPA<\/span>\u53d7\u4f53\u7684\u8c37\u6c28\u9178\u6d3b\u6027\uff0c\u51cf\u5c11\u4e0e\u766b\u75eb\u53d1\u4f5c\u76f8\u5173\u7684\u795e\u7ecf\u5143\u7684\u8fc7\u5ea6\u5174\u594b\u3002\u5421\u4ed1\u5e15\u5948\u7247\u5242\u88c5\u5df2\u4e0a\u5e02\u9500\u552e\uff0c\u6bcf\u65e5\u4e00\u6b21\uff0c\u7761\u524d\u53e3\u670d\u3002\u6b64\u5916\uff0c\u8be5\u836f\u7684\u53e3\u670d\u60ac\u6d6e\u5236\u5242\u5df2\u88ab\u6279\u51c6\u5728\u7f8e\u56fd\u4e0a\u5e02\u9500\u552e\u3002<\/p>\n<p>\u76ee\u524d\uff0c\u5421\u4ed1\u5e15\u5948\u5df2\u5728\u6b27\u6d32\u548c\u4e9a\u6d32\u8d85\u8fc7<span lang=\"EN-US\">55<\/span>\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\uff08\u5305\u62ec\u7f8e\u56fd\u548c\u65e5\u672c\uff09\u83b7\u5f97\u6279\u51c6\uff0c\u7528\u4e8e\u52a0\u7528\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u766b\u75eb\u60a3\u8005\u7684\u90e8\u5206\u6027\u53d1\u4f5c\uff08\u4f34\u6216\u4e0d\u4f34\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff09\u3002\u536b\u6750\u4e5f\u5728\u4e2d\u56fd\u63d0\u4ea4\u4e86\u5c06\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u65b0\u836f\u7533\u8bf7\u3002\u53e6\u5916\uff0c\u5421\u4ed1\u5e15\u5948\u5df2\u5728\u6b27\u6d32\u548c\u4e9a\u6d32\u7684<span lang=\"EN-US\">50<\/span>\u591a\u4e2a\u56fd\u5bb6\uff08\u5305\u62ec\u7f8e\u56fd\u3001\u65e5\u672c\u3001\u6b27\u6d32\u548c\u4e9a\u6d32\uff09\u83b7\u5f97\u6279\u51c6\uff0c\u7528\u4e8e\u52a0\u7528\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u766b\u75eb\u60a3\u8005\u7684\u539f\u53d1\u6027\u5168\u9762\u6027\u5f3a\u76f4\u9635\u631b\u53d1\u4f5c\u3002\u5728\u7f8e\u56fd\uff0c\u5421\u4ed1\u5e15\u5948\u5df2\u83b7\u51c6\u7528\u4e8e<span lang=\"EN-US\">4<\/span>\u5c81\u53ca\u4ee5\u4e0a\u60a3\u8005\u7684\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\uff08\u4f34\u6216\u4e0d\u4f34\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff09\u7684\u5355\u836f\u53ca\u52a0\u7528\u6cbb\u7597\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u536b\u6750\u6b63\u5728\u5168\u7403\u8303\u56f4\u5185\u8fdb\u884c\u4e00\u9879<span lang=\"EN-US\">III<\/span>\u671f\u4e34\u5e8a\u7814\u7a76\uff08<span lang=\"EN-US\">338<\/span>\u7814\u7a76\uff09\uff0c\u610f\u5728\u5c06\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u4e0e<span lang=\"EN-US\">Lennox-Gastaut<\/span>\u7efc\u5408\u5f81\u76f8\u5173\u7684\u766b\u75eb\u53d1\u4f5c\u3002\u536b\u6750\u6b63\u5728\u65e5\u672c\u548c\u6b27\u6d32\u8fdb\u884c\u4e00\u9879\u9488\u5bf9\u513f\u7ae5\u766b\u75eb\u60a3\u8005\u7684<span lang=\"EN-US\">III<\/span>\u671f\u7814\u7a76\uff08<span lang=\"EN-US\">311<\/span>\u7814\u7a76\uff09\u3002\u6b64\u5916\uff0c\u65e5\u672c\u6b63\u5728\u5f00\u5c55\u4e00\u9879\u5421\u4ed1\u5e15\u5948\u5355\u836f\u6cbb\u7597<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u672a\u7ecf\u6cbb\u7597\u7684\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7684<span lang=\"EN-US\">III<\/span>\u671f\u7814\u7a76\uff08<span lang=\"EN-US\">342<\/span>\u7814\u7a76\uff09\u3002<\/p>\n<p><span lang=\"EN-US\">\u00a0<\/span><\/p>\n<p><span class=\"a0\"><b><span lang=\"EN-US\">2<\/span><\/b><\/span><span class=\"a0\"><b>\u3001\u5173\u4e8e<span lang=\"EN-US\">335<\/span>\u7814\u7a76\uff08\u8be5\u65b0\u836f\u7533\u8bf7\u7684\u8bd5\u9a8c\u57fa\u7840\uff09<\/b><\/span><strong><sup><span lang=\"EN-US\">3<\/span><\/sup><\/strong><\/p>\n<p>\u7814\u7a76\u9898\u76ee\uff1a\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u53cc\u76f2\u3001\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u5e73\u884c\u7ec4\u7814\u7a76\uff0c \u65e8\u5728\u8bc4\u4ef7\u5421\u4ed1\u5e15\u5948\u7528\u4e8e\u52a0\u7528\u6cbb\u7597\u96be\u4ee5\u6cbb\u6108\u7684\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/p>\n<p>\u7814\u7a76\u4eba\u7fa4\uff1a<span lang=\"EN-US\">710<\/span>\u4f8b\u5e74\u9f84\u4e3a<span lang=\"EN-US\">12<\/span>\u5c81\u53ca\u4ee5\u4e0a\u4e14\u786e\u8bca\u4e3a\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u60a3\u8005\uff0c\u4f34\u6216\u4e0d\u4f34\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff0c\u63a5\u53d7\u8fc7\u4e00\u81f3\u4e09\u79cd\u6297\u766b\u75eb\u836f\u7269\u6cbb\u7597<\/p>\n<p>\u6cbb\u7597\u65b9\u6cd5\uff1a\u5421\u4ed1\u5e15\u5948\u53e3\u670d\u7247\uff0c\u5242\u91cf\u4e3a<span lang=\"EN-US\">4<\/span>\u6beb\u514b<span lang=\"EN-US\">\/<\/span>\u5929\uff0c<span lang=\"EN-US\">8<\/span>\u6beb\u514b<span lang=\"EN-US\">\/<\/span>\u5929\u548c<span lang=\"EN-US\">12<\/span>\u6beb\u514b<span lang=\"EN-US\">\/<\/span>\u5929\uff0c\u6bcf\u65e5\u4e00\u6b21\uff0c\u7761\u524d\u670d\u7528<\/p>\n<p>\u4e0e\u5421\u4ed1\u5e15\u5948\u76f8\u5bf9\u5e94\u7684\u5b89\u6170\u5242\u53e3\u670d\u7247\uff0c\u6bcf\u65e5\u4e00\u6b21\uff0c\u7761\u524d\u670d\u7528<\/p>\n<p>\u6cbb\u7597\u6301\u7eed\u65f6\u95f4\uff1a\u968f\u673a\u5206\u7ec4\u524d\u9636\u6bb5\uff1a<span lang=\"EN-US\">6<\/span>\u5468<\/p>\n<p><span lang=\"EN-US\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0 <\/span>\u968f\u673a\u5206\u7ec4\u9636\u6bb5\uff08\u6cbb\u7597\u9636\u6bb5\uff09\uff1a<span lang=\"EN-US\">19<\/span>\u5468<\/p>\n<p><span lang=\"EN-US\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0 \u00a0 <\/span>\uff08\u6ef4\u5b9a\u671f<span lang=\"EN-US\">6<\/span>\u5468\uff1b\u7ef4\u6301\u671f<span lang=\"EN-US\">13<\/span>\u5468\uff09<\/p>\n<p><span lang=\"EN-US\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span>\u5ef6\u957f\u671f\uff1a\u8d85\u8fc7<span lang=\"EN-US\">10<\/span>\u5468<\/p>\n<p>\u7814\u7a76\u5730\u70b9\uff1a\u65e5\u672c\u3001\u4e2d\u56fd\u5927\u9646\u3001\u97e9\u56fd\u3001\u6fb3\u5927\u5229\u4e9a\u3001\u6cf0\u56fd\u3001\u9a6c\u6765\u897f\u4e9a\u3001\u4e2d\u56fd\u53f0\u6e7e<\/p>\n<p>\u4e3b\u8981\u7ec8\u70b9\uff1a\u4e0e\u57fa\u7ebf\u76f8\u6bd4\uff0c\u6cbb\u7597\u671f\u95f4\u6bcf<span lang=\"EN-US\">28<\/span>\u5929\u53d1\u4f5c\u9891\u7387\u7684\u767e\u5206\u6bd4\u53d8\u5316<\/p>\n<p>\u7ed3\u679c\uff1a\u5b89\u6170\u5242\u7ec4\u7684\u53d1\u4f5c\u9891\u7387\u767e\u5206\u6bd4\u53d8\u5316\u4e3a<span lang=\"EN-US\">-10.8%<\/span>\uff0c\u800c\u5421\u4ed1\u5e15\u5948\uff08<span lang=\"EN-US\">4<\/span>\u6beb\u514b\uff0c<span lang=\"EN-US\">8<\/span>\u6beb\u514b\uff0c<span lang=\"EN-US\">12<\/span>\u6beb\u514b\uff09\u7ec4\u5206\u522b\u4e3a<span lang=\"EN-US\">-17.3%<\/span>\uff0c<span lang=\"EN-US\">-29.0%\u00a0<\/span>\u548c<span lang=\"EN-US\">-38.0%<\/span>\u3002\u5421\u4ed1\u5e15\u5948<span lang=\"EN-US\">8mg<\/span>\u548c<span lang=\"EN-US\">12mg<\/span>\u7ec4\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u6709\u7edf\u8ba1\u5b66\u4e0a\u7684\u663e\u8457\u5dee\u5f02<span lang=\"EN-US\">(8mg<\/span>\u7ec4<span lang=\"EN-US\">p=0.0003,12mg<\/span>\u7ec4<span lang=\"EN-US\">p&lt;0.0001)<\/span>\u3002<\/p>\n<p>\u4e0d\u826f\u53cd\u5e94\uff1a\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\uff08\u5728\u5421\u4ed1\u5e15\u5948\u7ec4\u4e2d\u7684\u51fa\u73b0\u7387<span lang=\"EN-US\">\u226510%<\/span>\uff0c\u4e14\u8f83\u5b89\u6170\u5242\u7ec4\u591a\u89c1\uff09\u4e3a\u5934\u6655\uff08\u5421\u4ed1\u5e15\u5948<span lang=\"EN-US\">4mg<\/span>\u3001<span lang=\"EN-US\">8mg<\/span>\u3001<span lang=\"EN-US\">12mg<\/span>\u7ec4\u5206\u522b\u4e3a<span lang=\"EN-US\">22.7%<\/span>\u3001<span lang=\"EN-US\">28.6%<\/span>\u3001<span lang=\"EN-US\">42.2%<\/span>\uff1b\u5b89\u6170\u5242\u7ec4\u4e3a<span lang=\"EN-US\">5.7%<\/span>\uff09\u548c\u55dc\u7761\uff08\u5421\u4ed1\u5e15\u5948<span lang=\"EN-US\">4mg<\/span>\u3001<span lang=\"EN-US\">8mg<\/span>\u3001<span lang=\"EN-US\">12mg<\/span>\u7ec4\u5206\u522b\u4e3a<span lang=\"EN-US\">15.9%<\/span>\u3001<span lang=\"EN-US\">17.7%<\/span>\u548c<span lang=\"EN-US\">17.8%<\/span>\uff1b\u5b89\u6170\u5242\u7ec4\u4e3a<span lang=\"EN-US\">13.1%<\/span>\uff09\u3002<\/p>\n<p><span lang=\"EN-US\">\u00a0<\/span><\/p>\n<p><b><span lang=\"EN-US\">3<\/span><\/b><b>\u3001\u5173\u4e8e\u766b\u75eb<\/b><\/p>\n<p>\u7f8e\u56fd\u7ea6\u6709<span lang=\"EN-US\">340<\/span>\u4e07\u766b\u75eb\u60a3\u8005\uff0c\u65e5\u672c\u7ea6\u6709<span lang=\"EN-US\">100<\/span>\u4e07\uff0c\u6b27\u6d32\u7ea6\u6709<span lang=\"EN-US\">600<\/span>\u4e07\uff0c\u4e2d\u56fd\u7ea6\u6709<span lang=\"EN-US\">900<\/span>\u4e07\uff0c\u800c\u5168\u4e16\u754c\u7ea6\u6709<span lang=\"EN-US\">6,000<\/span>\u4e07\u60a3\u8005\u3002\u5927\u7ea6<span lang=\"EN-US\">30%<\/span>\u7684\u766b\u75eb\u60a3\u8005\u4f7f\u7528\u73b0\u6709\u7684\u6297\u766b\u75eb\u836f\u7269\u4e0d\u80fd\u63a7\u5236\u75c5\u60c5<span lang=\"EN-US\">,<\/span>\u766b\u75eb\u662f\u4e00\u79cd\u533b\u7597\u9700\u6c42\u4e25\u91cd\u672a\u88ab\u6ee1\u8db3\u7684\u75be\u75c5<sup><span lang=\"EN-US\">2<\/span><\/sup>\u3002<\/p>\n<p>\u766b\u75eb\u6309\u53d1\u4f5c\u7c7b\u578b\u5206\u7c7b\uff0c\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u7ea6\u5360\u766b\u75eb\u75c5\u4f8b\u7684<span lang=\"EN-US\">60<\/span>\uff05\uff0c\u5168\u9762\u6027\u53d1\u4f5c\u7ea6\u5360<span lang=\"EN-US\">40<\/span>\uff05\u3002\u5728\u766b\u75eb\u90e8\u5206\u6027\u53d1\u4f5c\u4e2d\uff0c\u5f02\u5e38\u7535\u5e72\u6270\u53d1\u751f\u5728\u5927\u8111\u7684\u6709\u9650\u533a\u57df\uff0c\u5e76\u53ef\u80fd\u968f\u540e\u6269\u6563\u5230\u6574\u4e2a\u8111\u90e8\uff0c\u6210\u4e3a\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff08\u79f0\u4e3a\u7ee7\u53d1\u6027\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\uff09\u3002\u5728\u5168\u9762\u6027\u766b\u75eb\u53d1\u4f5c\u4e2d\uff0c\u5f02\u5e38\u7535\u5e72\u6270\u53d1\u751f\u5728\u6574\u4e2a\u8111\u90e8\uff0c\u968f\u540e\u53ef\u80fd\u51fa\u73b0\u610f\u8bc6\u4e27\u5931\u6216\u51fa\u73b0\u5168\u8eab\u75c7\u72b6\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><sup>1<\/sup>\u00a0 Clinical Guideline 2015 in China<br \/>\n<sup>2<\/sup>\u00a0 &#8220;The Epilepsies and Seizures: Hope Through Research. What are the epilepsies?&#8221; National Institute of Neurological Disorders and Stroke, accessed May 24, 2016,\u00a0<a href=\"http:\/\/www.ninds.nih.gov\/disorders\/epilepsy\/detail_epilepsy.htm#230253109\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.ninds.nih.gov\/disorders\/epilepsy\/detail_epilepsy.htm#230253109<\/a><br \/>\n<sup>3<\/sup>\u00a0 Nishida T., et al. Adjunctive perampanel in partial-onset seizures: Asia-Pacific, randomized phase III study.\u00a0<i>Acta Neurol Scand.<\/i>\u00a02018; 137:392-399<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u5ba3\u5e03\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u63a5\u53d7\u536b\u6750\u4e2d\u56fd\u63d0\u4ea4\u7684\u5c06\u6297\u766b\u75eb\u836f\u7269\u5421\u4ed1\u5e15\u5948\uff08\u901a\u7528\u540d\uff0c\u5546\u54c1\u540d\uff1aFycompa\uff09\u7528\u4e8e\u52a0\u7528\u6cbb\u759712\u5c81\u53ca\u4ee5\u4e0a\u766b\u75eb\u60a3\u8005\u7684\u90e8\u5206\u6027\u53d1\u4f5c\u7684\u65b0\u836f\u7533\u8bf7\uff0c\u5e76\u8fdb\u884c\u5ba1\u8bc4\u3002\u8fd9\u662f\u536b\u6750\u7b2c\u4e00\u6b21\u5728\u4e2d\u56fd\u63d0\u4ea4\u5421\u4ed1\u5e15\u5948\u7684\u65b0\u836f\u7533\u8bf7\u3002<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-3224","post","type-post","status-publish","format-standard","hentry","category-news-zh"],"_links":{"self":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3224"}],"collection":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/comments?post=3224"}],"version-history":[{"count":3,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3224\/revisions"}],"predecessor-version":[{"id":6002,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3224\/revisions\/6002"}],"wp:attachment":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/media?parent=3224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/categories?post=3224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/tags?post=3224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}