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\u6211\u4eec\u8fd8\u5bf9BELVIQ\u00a0\u7684\u7597\u6548\u8fdb\u884c\u4e86\u63a2\u7d22\u6027\u8bc4\u4f30\u3002\u5728\u4e00\u5e74\u7684\u65f6\u95f4\u91cc\uff0c\u4e0e\u670d\u7528\u5b89\u6170\u5242\u7684\u60a3\u8005\u76f8\u6bd4\uff0c\u670d\u7528BELVIQ\u00a0\u7684\u60a3\u8005\u4e2d\uff0c\u4f53\u91cd\u51cf\u8f7b5%\u53ca\u4ee5\u4e0a\u7684\u60a3\u8005\u6570\u91cf\uff0839% vs. 17%;\u540d\u4e49P\u503c<0.001\uff09\u548c\u4f53\u91cd\u51cf\u8f7b10%\u53ca\u4ee5\u4e0a\u7684\u60a3\u8005\u6570\u91cf\uff0815% vs. 5%\uff1b\u540d\u4e49P\u503c<0.001)\uff09\u660e\u663e\u66f4\u591a\u3002<\/p>\n

\u4e0e\u57fa\u7ebf\u6570\u636e\u76f8\u6bd4\uff0cBELVIQ\u7ec4\u60a3\u8005\u7684\u5e73\u5747\u4f53\u91cd\u53d8\u5316\u4e3a-4.2 kg\u00a0\uff0c\u5b89\u6170\u5242\u7ec4\u4e3a-1.4 kg\u3002\u4e5f\u5c31\u662f\u8bf4\uff0cBELVIQ\u7ec4\u7684\u4f53\u91cd\u51cf\u8f7b\u51c0\u503c\u8981\u591a\u51fa2.8 kg\uff08\u540d\u4e49P\u503c<0.001\uff09\u3002<\/p>\n

\u6b64\u5916\uff0c\u5728CAMELLIA-TIMI 61\u8bd5\u9a8c\u4e2d\uff0c\u5728\u5bf9\u5404\u79cd\u5171\u75c5\u8fdb\u884c\u9876\u7ea7\u62a4\u7406\u7684\u6761\u4ef6\u4e0b\uff0c\u63a5\u53d7BELVIQ\u6cbb\u7597\uff08\u4e3a\u671f\u4e00\u5e74\uff09\u4e0e\u4ee5\u4e0b\u7edf\u8ba1\u5b66\u4e0a\u7684\u663e\u8457\u6539\u5584\u76f8\u5173\uff1a\u6536\u7f29\u538b\uff08\u4e0e\u5b89\u6170\u5242\u7ec4\u7684\u5dee\u989d\u4e3a-0.9 mm Hg\uff09\uff0c\u8212\u5f20\u538b\uff08-0.8 mm Hg\uff09\uff0c\u5fc3\u7387\uff08\u6bcf\u5206\u949f-1.0\u00a0\u6b21\uff09\uff0c\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\uff08-1.2 mg\/dL\uff09\uff0c\u7518\u6cb9\u4e09\u916f\uff08-11.7 mg\/dL\uff09\u548c\u975e\u9ad8\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\uff08-2.6 mg\/dL\uff09\u3002<\/p>\n

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\u66f4\u591a\u5173\u4e8e\u8be5\u7814\u7a76\u7684\u5206\u6790\u7ed3\u679c\u5c06\u572810\u67084\u65e5\u4e8e\u5fb7\u56fd\u67cf\u6797\u4e3e\u884c\u7684\u6b27\u6d32\u7cd6\u5c3f\u75c5\u7814\u7a76\u534f\u4f1a\uff08EASD\uff09\u5e74\u4f1a\u4e0a\u53d1\u5e03\u3002<\/p>\n

\u536b\u6750\u5c06\u9646\u7eed\u63d0\u4f9b\u66f4\u591a\u6709\u5173BELVIQ\u7684\u4e34\u5e8a\u548c\u79d1\u5b66\u4fe1\u606f\uff0c\u4e3a\u89e3\u51b3\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u548c\u63d0\u9ad8\u60a3\u8005\u53ca\u5176\u5bb6\u5c5e\u7684\u798f\u7949\u505a\u51fa\u8d21\u732e\u3002<\/p>\n

<\/p>\n

\u5a92\u4f53\u54a8\u8be2\uff1a<\/strong><\/b>
\n\u536b\u6750\u682a\u5f0f\u4f1a\u793e
\n\u516c\u5173\u90e8
\n+81-(0)3-3817-5120<\/p>\n

<\/p>\n

[\u7f16\u8005\u6309]<\/strong>
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\n\u6b64\u5916\uff0cBELVIQ XR\u662f\u6c2f\u5361\u8272\u6797\u7684\u6bcf\u65e5\u4e00\u6b21\u5242\u578b\uff0c\u65e8\u5728\u4f7f\u60a3\u8005\u670d\u836f\u66f4\u52a0\u65b9\u4fbf\uff0c\u7f8e\u56fd\u57282016\u5e747\u6708\u6279\u51c6\u4e86\u8be5\u5236\u5242\u3002
\n2017\u5e741\u6708\uff0c\u536b\u6750\u83b7\u5f97Arena\u5f00\u53d1\u548c\u8425\u9500\u6c2f\u5361\u8272\u6797\u7684\u5168\u90e8\u6743\u5229\u3002
\n\u5728\u591a\u4e2a\u9488\u5bf9\u6c2f\u5361\u8272\u6797\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u975e\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u4e3a\u5934\u75db\u3001\u5934\u6655\u3001\u75b2\u52b3\u3001\u6076\u5fc3\u3001\u53e3\u5e72\u548c\u4fbf\u79d8\uff0c\u800c\u5728\u7cd6\u5c3f\u75c5\u60a3\u8005\u4e2d\u7684\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u4e3a\u4f4e\u8840\u7cd6\u3001\u5934\u75db\u3001\u80cc\u75db\u3001\u54b3\u55fd\u548c\u75b2\u52b3\u3002\u4e86\u89e3\u66f4\u591a\u6c2f\u5361\u8272\u6797\u5728\u7f8e\u56fd\u7684\u4fe1\u606f\uff0c\u5305\u62ec\u91cd\u8981\u5b89\u5168\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eeBELVIQ\u4ea7\u54c1\u7f51\u7ad9(http:\/\/www.belviq.com<\/a>)\u3002<\/p>\n

2<\/strong>. \u5173\u4e8e\u5fc3\u8840\u7ba1\u7ed3\u5c40\u8bd5\u9a8c\u2014\u2014CAMELLIA-TIMI61\u7814\u7a76<\/strong>
\n<\/strong>CAMELLIA\uff08\u6c2f\u5361\u8272\u6797\u5bf9\u8d85\u91cd\u548c\u80a5\u80d6\u60a3\u8005\u7684\u5fc3\u8840\u7ba1\u548c\u4ee3\u8c22\u65b9\u9762\u7684\u5f71\u54cd\uff09TIMI 61\u7814\u7a76\u662f\u5728\u51cf\u80a5\u836f\u7269\u4e2d\u8fdb\u884c\u7684\u6700\u5927\u7684\u53cc\u76f2\u3001\u5b89\u6170\u5242\u5bf9\u7167\u3001\u5e73\u884c\u7ec4\u00a0IIIB\/IV\u00a0\u671f\u7814\u7a76\u3002\u7814\u7a76\u7684\u4e3b\u8981\u5b89\u5168\u76ee\u6807\u662f\u8bc4\u4f30\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff09\u7684\u53d1\u751f\u7387\u3002\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u5305\u62ec\u5fc3\u8840\u7ba1\u75be\u75c5\u5bfc\u81f4\u7684\u6b7b\u4ea1\u3001\u5fc3\u808c\u6897\u6b7b\u6216\u4e2d\u98ce\u3002\u5728\u8fbe\u5230\u4e3b\u8981\u5b89\u5168\u76ee\u6807\u7684\u57fa\u7840\u4e0a\uff0c\u5176\u7597\u6548\u76ee\u6807\u662f\u8bc4\u4f30\u6c2f\u5361\u8272\u6797\u5bf9MACE+\u00a0\u53d1\u751f\u7387\u7684\u5f71\u54cd\u3002MACE+\u7684\u5b9a\u4e49\u662fMACE\u6216\u56e0\u4e0d\u7a33\u5b9a\u578b\u5fc3\u7ede\u75db\u6216\u5fc3\u529b\u8870\u7aed\u4f4f\u9662\uff0c\u6216\u4efb\u4f55\u51a0\u72b6\u52a8\u8109\u518d\u8840\u7ba1\u5316\u3002\u6b21\u8981\u76ee\u6807\u5305\u62ec\u8bc4\u4f30\u5ef6\u8fdf\u6216\u963b\u6b62\u7cd6\u5c3f\u75c5\u524d\u671f\u60a3\u8005\u6216\u5728\u57fa\u7ebf\u65f6\u65e0\u7cd6\u5c3f\u75c5\u7684\u60a3\u8005\u8f6c\u5316\u4e3aT2DM\u7684\u53ef\u80fd\u6027\uff0c\u4ee5\u53ca\u5bf9T2DM\u00a0\u60a3\u8005\u5728\u8840\u7cd6\u63a7\u5236\u65b9\u9762\u7684\u6539\u5584<\/p>\n

\uff13. \u5173\u4e8eTIMI\u7814\u7a76\u7ec4
\n<\/strong>TIMI\u7814\u7a76\u7ec4\u662f\u5e03\u5217\u6839\u548c\u5987\u5973\u533b\u9662\uff08Brigham and Women\u2019s Hospital\uff09\u7684\u4e00\u4e2a\u5b66\u672f\u7814\u7a76\u673a\u6784\uff0c\u5df2\u5f15\u9886\u6539\u53d8\u5b9e\u8df5\u7684\u5fc3\u8840\u7ba1\u4e34\u5e8a\u8bd5\u9a8c\u8fbe30\u5e74\u4e4b\u4e45\u3002<\/p>\n

\uff14. \u5173\u4e8e\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b
\n<\/strong>\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\uff08NEJM\uff09\u300b\u662f\u4e00\u5bb6\u4e16\u754c\u9886\u5148\u7684\u533b\u5b66\u671f\u520a\uff0c\u8bbe\u6709\u7f51\u7ad9\u3002\u5176\u671f\u520a\u5df2\u51fa\u7248\u4e86200\u591a\u5e74\u3002\u5728\u6240\u6709\u7efc\u5408\u7c7b\u533b\u5b66\u671f\u520a\u4e2d\uff0cNEJM\u7684\u671f\u520a\u5f71\u54cd\u6307\u6570\uff08Journal Impact Factor\uff09\u9996\u5c48\u4e00\u6307\uff082017\u671f\u520a\u5f15\u7528\u62a5\u544a<\/em>^{\u00ae<\/sup><\/em>\uff0cClarivate Analytics\uff0c2018\uff09\u3002<\/p>\n}

\u00a0<\/span><\/p>\n

^{1<\/sup>\u00a0Bohula, E. A., Cardiovascular Safety of Lorcaserin in Overweight and Obese Patients, The\u00a0New England Journal of Medicine<\/em>,\u00a02018.<\/p>\n","protected":false},"excerpt":{"rendered":"}