{"id":3547,"date":"2017-06-05T00:00:00","date_gmt":"2017-06-05T03:15:19","guid":{"rendered":"https:\/\/www.eisai.com.cn\/?p=3547"},"modified":"2021-04-08T11:25:33","modified_gmt":"2021-04-08T03:25:33","slug":"%e5%8d%ab%e6%9d%90%e5%9c%a8%e7%ac%ac53%e5%b1%8a%e7%be%8e%e5%9b%bd%e4%b8%b4%e5%ba%8a%e8%82%bf%e7%98%a4%e5%ad%a6%e4%bc%9a%ef%bc%88asco%ef%bc%89%e5%b9%b4%e4%bc%9a%e5%8f%a3%e5%a4%b4%e6%b1%87%e6%8a%a5lenvi","status":"publish","type":"post","link":"https:\/\/www.eisai.com.cn\/2017\/06\/05\/%e5%8d%ab%e6%9d%90%e5%9c%a8%e7%ac%ac53%e5%b1%8a%e7%be%8e%e5%9b%bd%e4%b8%b4%e5%ba%8a%e8%82%bf%e7%98%a4%e5%ad%a6%e4%bc%9a%ef%bc%88asco%ef%bc%89%e5%b9%b4%e4%bc%9a%e5%8f%a3%e5%a4%b4%e6%b1%87%e6%8a%a5lenvi\/","title":{"rendered":"\u536b\u6750\u5728\u7b2c53\u5c4a\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u5e74\u4f1a\u53e3\u5934\u6c47\u62a5LENVIMA\u00ae\uff08\u4e50\u4f10\u66ff\u5c3c\uff09\u4e00\u7ebf\u6cbb\u7597\u4e0d\u53ef\u5207\u9664\u7684\u809d\u7ec6\u80de\u764c\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c"},"content":{"rendered":"

\u540c\u7d22\u62c9\u975e\u5c3c\u76f8\u6bd4\uff0c\u8bd5\u9a8c\u7ed3\u679c\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\uff0c\u6b21\u8981\u7ec8\u70b9\u6709\u660e\u663e\u6539\u5584\uff0c\u4e14\u6570\u636e\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49<\/em><\/p>\n

<\/p>\n

\u6839\u636e\u7814\u7a76\u7ed3\u679c\uff0c\u4e50\u4f10\u66ff\u5c3c\uff0813.6\u4e2a\u6708\uff09\u540c\u7d22\u62c9\u975e\u5c3c\uff0812.3\u4e2a\u6708\uff09\u76f8\u6bd4\uff0c\u5728\u4e3b\u8981\u7ec8\u70b9\uff0c\u5373\u4e2d\u4f4d\u603b\u751f\u5b58\u65b9\u9762\uff0c\u8fbe\u5230\u975e\u52a3\u6548\u6027\u7684\u7edf\u8ba1\u6807\u51c6\u3002\uff08\u98ce\u9669\u6bd4\uff08HR\uff09\u4e3a0.92\uff0c95%\u7f6e\u4fe1\u533a\u95f4\u00a0[CI] = 0.79-1.06\uff09\u3002<\/p>\n

\u6b64\u5916\uff0c\u540c\u7d22\u62c9\u975e\u5c3c\u76f8\u6bd4\uff0c\u4e50\u4f10\u66ff\u5c3c\u5728\u4e09\u4e2a\u6b21\u8981\u7ec8\u70b9\u65b9\u9762\uff0c\u5373\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff08\u4e50\u4f10\u66ff\u5c3c7.4\u4e2a\u6708\uff0c\u7d22\u62c9\u975e\u5c3c3.7\u4e2a\u6708\uff0c\u98ce\u9669\u6bd4\uff08HR\uff09\u4e3a0.66\uff0c95%\u7f6e\u4fe1\u533a\u95f4[CI] = 0.57-0.77\uff0cP<0.00001\uff09\uff0c\u4e2d\u4f4d\u75be\u75c5\u8fdb\u5c55\u65f6\u95f4\uff08\u4e50\u4f10\u66ff\u5c3c8.9\u4e2a\u6708\uff0c\u7d22\u62c9\u975e\u5c3c3.7\u4e2a\u6708\uff0c\u98ce\u9669\u6bd4\uff08HR\uff09\u4e3a0.63\uff0c95%\u7f6e\u4fe1\u533a\u95f4\u00a0[CI]= 0.53-0.73\uff0cP<0.00001\uff09\uff0c\u5176\u6539\u5584\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\u3002\u603b\u6709\u6548\u7387\u4e3a\uff08\u4e50\u4f10\u66ff\u5c3c24%\uff0c\u7d22\u62c9\u975e\u5c3c9%\uff0cP<0.00001\uff09\u3002<\/p>\n

\u6b64\u5916\uff0c\u6b27\u6d32\u764c\u75c7\u6cbb\u7597\u7814\u7a76\u7ec4\u7ec7\u7684\u751f\u6d3b\u8d28\u91cf\u8c03\u67e5\u95ee\u5377-C30\uff08EORTC QLQ-C30\uff09\u5bf9\u60a3\u8005\u8fdb\u884c\u7684\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\uff08QOL\uff09\u8bc4\u4f30\u663e\u793a\uff0c\u540c\u7d22\u62c9\u975e\u5c3c\u76f8\u6bd4\uff0c\u4e50\u4f10\u66ff\u5c3c\u6709\u52a9\u4e8e\u63a8\u8fdf\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\u7684\u6076\u5316\uff0c\u8bf8\u5982\u51fa\u73b0\u75bc\u75db\u3001\u8179\u6cfb\u7b49\uff08\u540d\u4e49P\u503c\uff1c0.05\uff09\u3002<\/p>\n

\u5728\u672c\u6b21\u7814\u7a76\u4e2d\u6240\u89c2\u5bdf\u5230\u7684\u4e50\u4f10\u66ff\u5c3c\u7684\u4e94\u79cd\u6700\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u4e3a\uff1a\u9ad8\u8840\u538b\u3001\u8179\u6cfb\u3001\u98df\u6b32\u4e0b\u964d\u3001\u4f53\u91cd\u51cf\u8f7b\u3001\u75b2\u52b3\uff0c\u8fd9\u540c\u4e50\u4f10\u66ff\u5c3c\u5df2\u77e5\u7684\u526f\u4f5c\u7528\u4e00\u81f4\u3002<\/p>\n

\u57fa\u672c\u8be5\u9879\u7814\u7a76\u7ed3\u679c\uff0c\u536b\u6750\u5c06\u57282017\u8d22\u5e74\u7684\u4e0a\u534a\u5e74\u5411\u65e5\u672c\u3001\u7f8e\u56fd\u548c\u6b27\u6d32\u63d0\u4ea4\u4e50\u4f10\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597\u809d\u7ec6\u80de\u764c\u7684\u76d1\u7ba1\u7533\u8bf7\uff0c\u5e76\u57282017\u8d22\u5e74\u5185\u5411\u4e2d\u56fd\u63d0\u4ea4\u7533\u8bf7\u3002<\/p>\n

\u809d\u764c\u662f\u764c\u75c7\u76f8\u5173\u6b7b\u4ea1\u7684\u7b2c\u4e8c\u5927\u539f\u56e0\uff0c\u5168\u7403\u6bcf\u5e74\u7ea6\u6709750000\u4eba\u6b7b\u4e8e\u8be5\u75c5\u3002\u6b64\u5916\uff0c\u6bcf\u5e74\u65b0\u786e\u8bca\u7684\u809d\u764c\u75c5\u4f8b\u4e3a780000\u4f8b\uff0c\u5176\u4e2d\u7ea680%\u53d1\u751f\u5728\u4e9a\u6d32\u5730\u533a\uff0c\u5305\u62ec\u65e5\u672c\u548c\u4e2d\u56fd\u3002\u809d\u7ec6\u80de\u764c\u5360\u539f\u53d1\u6027\u809d\u764c\u75c5\u4f8b\u768485%\u523090%\u3002\u65e9\u671f\u7684\u809d\u7ec6\u80de\u764c\u53ef\u4ee5\u901a\u8fc7\u5404\u79cd\u624b\u6bb5\u6cbb\u6108\uff0c\u5305\u62ec\u624b\u672f\u3001\u5c04\u9891\u6d88\u878d\u3001\u65e0\u6c34\u9152\u7cbe\u6ce8\u5c04\u3001\u6813\u585e\u5316\u7597\u7b49\uff0c\u4f46\u5bf9\u4e8e\u4e0d\u53ef\u5207\u9664\u7684\u809d\u7ec6\u80de\u764c\uff0c\u53ef\u7528\u7684\u6cbb\u7597\u65b9\u6cd5\u662f\u6709\u9650\u7684\uff0c\u4e14\u9884\u540e\u5f88\u5dee\uff0c\u4e5f\u5c31\u662f\u8bf4\uff0c\u8be5\u9886\u57df\u4ecd\u5b58\u5728\u7740\u5927\u91cf\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002<\/p>\n

\u536b\u6750\u5c06\u80bf\u7624\u89c6\u4e3a\u516c\u53f8\u7684\u4e00\u4e2a\u5173\u952e\u6cbb\u7597\u9886\u57df\uff0c\u81f4\u529b\u4e8e\u7814\u53d1\u6709\u53ef\u80fd\u6cbb\u6108\u764c\u75c7\u7684\u9769\u547d\u6027\u65b0\u836f\u7269\u3002\u536b\u6750\u5c06\u7ee7\u7eed\u63a2\u7d22\u79d1\u5b66\u8bc1\u636e\uff0c\u4f7f\u4e50\u4f10\u66ff\u5c3c\u80fd\u591f\u5728\u672a\u6765\u6700\u5927\u9650\u5ea6\u5730\u6ee1\u8db3\u60a3\u8005\u591a\u6837\u5316\u7684\u9700\u6c42\uff0c\u5e76\u4e3a\u764c\u75c7\u60a3\u8005\u3001\u60a3\u8005\u5bb6\u5c5e\u53ca\u533b\u7597\u4ece\u4e1a\u8005\u5e26\u6765\u66f4\u591a\u798f\u7949\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

6\u67085\u65e5\uff0c\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u4e1c\u4eac\uff0c\u73b0\u4efb\u793e\u957f\u4e3a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u5ba3\u5e03\uff0c\u5728\u7f8e\u56fd\u829d\u52a0\u54e5\u4e3e\u884c\u7684\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08ASCO\uff09\u7b2c53\u5c4a\u5e74\u4f1a\u4e0a\u53e3\u5934\u53d1\u5e03\u81ea\u4e3b\u7814\u53d1\u7684\u6297\u764c\u65b0\u836f\u00a0\u2014\u00a0\u7532\u78fa\u9178\u4e50\u4f10\u66ff\u5c3c\uff08lenvatinib mesylate\uff09\uff08\u5546\u54c1\u540d\uff1aLenvima\u00ae \/ Kisplyx\u00ae\uff0c\u201c\u4e50\u4f10\u66ff\u5c3c\u201d\uff09\u5bf9\u6bd4\u7d22\u62c9\u975e\u5c3c\u4e00\u7ebf\u7528\u4e8e\u4e0d\u53ef\u5207\u9664\u7684\u809d\u7ec6\u80de\u764c\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u679c\uff08304\u7814\u7a76\uff09\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u4e50\u4f10\u66ff\u5c3c\u662f\u7b2c\u4e00\u4e2a\u5728\u4e3b\u8981\u7ec8\u70b9\uff0c\u5373\u603b\u751f\u5b58\uff08OS\uff09\u65b9\u9762\uff0c\u5728\u7edf\u8ba1\u6570\u636e\u4e0a\u4e0d\u52a3\u4e8e\u7d22\u62c9\u975e\u5c3c\u7684\u6297\u764c\u5236\u5242\uff0c\u4e14\u5728\u6b21\u8981\u7ec8\u70b9\u2014\u2014\u5373\u65e0\u8fdb\u5c55\u751f\u5b58\uff08PFS\uff09\u3001\u75be\u75c5\u8fdb\u5c55\u65f6\u95f4\uff08TTP\uff09\u548c\u5ba2\u89c2\u53cd\u5e94\u7387\uff08ORR\uff09\u65b9\u9762\u6709\u663e\u8457\u6539\u5584\uff0c\u5176\u7ed3\u679c\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\u548c\u4e34\u5e8a\u610f\u4e49\uff0c\u5176\u4e2d\u4f4d\u503c\u548c\u6bd4\u7387\u5747\u8f83\u7d22\u62c9\u975e\u5c3c\u63d0\u9ad8\u4e86\u4e00\u500d\u3002<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-3547","post","type-post","status-publish","format-standard","hentry","category-news-zh"],"_links":{"self":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3547"}],"collection":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/comments?post=3547"}],"version-history":[{"count":2,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3547\/revisions"}],"predecessor-version":[{"id":3549,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/3547\/revisions\/3549"}],"wp:attachment":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/media?parent=3547"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/categories?post=3547"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/tags?post=3547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}