\u65e5\u672c\u4e1c\u4eac\u548c\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\uff0c2021\u5e7411\u670812\u65e5-\u536b\u6750\u682a\u5f0f\u4f1a\u793e\uff08\u603b\u90e8\uff1a\u4e1c\u4eac\uff0c\u9996\u5e2d\u6267\u884c\u5b98\uff1a\u5185\u85e4\u6674\u592b\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u536b\u6750\u201d\uff09\u548c\u6e24\u5065\u516c\u53f8\uff08Nasdaq\uff1aBIIB\uff0c\u603b\u90e8\uff1a\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02\uff0c\u9996\u5e2d\u6267\u884c\u5b98\uff1aMichel Vounatsos\uff0c\u4ee5\u4e0b\u7b80\u79f0\u201c\u6e24\u5065\u201d\uff09\u5ba3\u5e03\u4e86\u4e00\u9879\u63a2\u7d22\u5728Lecanemab\uff08BAN2401\uff09\uff08\u4e00\u79cd\u8bd5\u9a8c\u6027\u6297\u6dc0\u7c89\u6837\u86cb\u767d\u03b2 [A\u03b2]\u539f\u7ea4\u7ef4\u6297\u4f53\uff09\u7684III\u671fAHEAD 3-45\u7814\u7a76\u4e2d\u4f7f\u7528\u8840\u6d46\u751f\u7269\u6807\u5fd7\u7269\u7684\u7814\u7a76\u6210\u679c\u3002AHEAD 3-45\u662f\u9996\u4e2a\u4f7f\u7528\u8fd9\u4e9b\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff08AD\uff09\u75c5\u7406\u5e76\u53ef\u80fd\u52a0\u901f\u7b5b\u67e5\u8fc7\u7a0b\u7684\u4e34\u5e8a\u524dAD\u8bd5\u9a8c\u3002\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u8054\u76df\uff08ACTC\uff09\u57282021\u5e7411\u67089\u65e5\u81f312\u65e5\u5728\u9a6c\u8428\u8bf8\u585e\u5dde\u6ce2\u58eb\u987f\u4e3e\u884c\u76842021\u5e74\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\uff08CTAD\uff09\u4f1a\u8bae\u4e0a\u5ba3\u5e03\u4e86\u6b64\u7814\u7a76\u6210\u679c\u3002<\/p>\n
AHEAD 3-45\u4e34\u5e8a\u7814\u7a76\u5c06\u5728\u4e34\u5e8a\u524dAD\u548c\u6dc0\u7c89\u6837\u86cb\u767d\u5347\u9ad8\u53d7\u8bd5\u8005\u4ee5\u53ca\u65e9\u671f\u4e34\u5e8a\u524dAD\u548c\u4e2d\u7b49\u6dc0\u7c89\u6837\u86cb\u767d\u53d7\u8bd5\u8005\u4e2d\u8bc4\u4ef7Lecanemab\u6cbb\u7597\u7684\u6709\u6548\u6027\u30022021\u5e749\u6708\uff0c\u536b\u6750\u5f00\u59cb\u901a\u8fc7\u52a0\u901f\u6279\u51c6\u901a\u9053\u5411\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6eda\u52a8\u63d0\u4ea4Lecanemab\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08BLA\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u65e9\u671fAD\u3002<\/p>\n
III\u671fAHEAD 3-45\u7814\u7a76\u5305\u62ec\u4e24\u9879\u59d0\u59b9\u8bd5\u9a8c\uff08A3\u548cA45\uff09\uff0c\u57fa\u4e8eA3\u4e2d\u4e2d\u7b49\u6dc0\u7c89\u6837\u86cb\u767d\u548cA45\u4e2d\u6dc0\u7c89\u6837\u86cb\u767d\u5347\u9ad8\u7684PET\u626b\u63cf\u7ed3\u679c\u7684\u57fa\u7ebf\u8111\u6dc0\u7c89\u6837\u86cb\u767d\u6c34\u5e73\uff0c\u91c7\u7528\u7279\u5b9a\u7684\u7ed9\u836f\u65b9\u6848\u8fdb\u884c\u7814\u7a76\u3002\u4f5c\u4e3a\u4e00\u9879\u4e34\u5e8a\u524dAD\u8bd5\u9a8c\u4e2d\u7684\u9996\u4e2a\u540c\u7c7b\u65b9\u6cd5\uff0c\u8be5\u7814\u7a76\u5c06\u81f4\u529b\u4e8e\u786e\u5b9a\u8840\u6d46\u751f\u7269\u6807\u5fd7\u7269\u5728\u8bc6\u522b\u6700\u9002\u5408\u63a5\u53d7\u6b63\u7535\u5b50\u53d1\u5c04\u65ad\u5c42\u6210\u50cf\uff08PET\uff09\uff08\u76ee\u524d\u786e\u5b9a\u6cbb\u7597\u65b9\u6cd5\u7684\u6807\u51c6\u6cbb\u7597\u65b9\u6cd5\uff09\u7684\u8ba4\u77e5\u672a\u53d7\u635f\u4e2a\u4f53\u7684\u6f5c\u5728\u4f5c\u7528\u3002<\/p>\n
\u5c06\u5728\u77ed\u6682\u7684\u521d\u59cb\u8bbf\u89c6\u65f6\u91c7\u96c6\u8840\u6837\uff0c\u4ee5\u786e\u5b9aA\u03b242\/40\u7684\u6bd4\u503c\uff0c\u5148\u524d\u7814\u7a76\u5df2\u8bc1\u660e\u8be5\u6bd4\u503c\u662f\u8111\u6dc0\u7c89\u6837\u86cb\u767d\u6c34\u5e73\u7684\u6f5c\u5728\u53ef\u9760\u9884\u6d4b\u56e0\u5b50\uff0c\u5e76\u53ef\u7528\u4e8e\u786e\u5b9a\u662f\u5426\u9002\u5408\u8fdb\u884cPET\u6210\u50cf\u3002\u6839\u636ePET\u6210\u50cf\u7ed3\u679c\uff0c\u5c06\u53d7\u8bd5\u8005\u5206\u81f3A3\u6216A45\u8bd5\u9a8c\u3002<\/p>\n
\u622a\u81f32021\u5e7410\u670818\u65e5\uff0c659\u4f8b\u53d7\u8bd5\u8005\u7684\u6570\u636e\u53ef\u7528\u4e8e\u5206\u6790\u3002\u6821\u6b63\u540e\u7684A\u03b242\/40\u6bd4\u503c\u9884\u6d4b\u662f\u5426\u9002\u5408\u6dc0\u7c89\u6837\u86cb\u767dPET\u7684\u80fd\u529b\u6781\u4f73\uff08AUC\u4e3a0.87\uff09\uff0c\u8868\u660e\u8840\u6d46\u7b5b\u67e5\u6709\u53ef\u80fd\u5927\u5e45\u51cf\u5c11\u5b8c\u5168\u5165\u7ec4A3\u548cA45\u6240\u9700\u7684PET\u626b\u63cf\u6b21\u6570\u3002<\/p>\n
\u536b\u6750\u526f\u603b\u88c1\u517c\u795e\u7ecf\u75c5\u5b66\u4e1a\u52a1\u526f\u9996\u5e2d\u4e34\u5e8a\u5b98Michael Irizarry\u535a\u58eb\u8868\u793a\uff1a\u201cAD\u7684\u7b5b\u67e5\u8fc7\u7a0b\u53ef\u80fd\u8d39\u65f6\u4e14\u6602\u8d35\u3002\u6709\u5fc5\u8981\u52a0\u901f\u548c\u63d0\u9ad8\u57fa\u4e8e\u8ba4\u77e5\u6d4b\u8bd5\u548c\u786e\u8ba4\u5927\u8111\u4e2d\u6dc0\u7c89\u6837\u86cb\u767d\u5347\u9ad8\u6765\u8bc6\u522b\u53ef\u80fd\u9002\u5408\u63a5\u53d7\u5f53\u524d\u548c\u672a\u6765AD\u6cbb\u7597\u7684\u4e2a\u4f53\u7684\u6548\u7387\u3002\u536b\u6750\u6b63\u5728\u901a\u8fc7\u5c06\u8840\u6d46\u7b5b\u67e5\u7eb3\u5165\u4e34\u5e8a\u524dAD\u4e2a\u4f53\u7684\u4e34\u5e8a\u7814\u7a76\u800c\u5f00\u62d3\u6cbb\u7597\u65b0\u5929\u5730\u3002\u6211\u4eec\u4e50\u89c2\u5730\u8ba4\u4e3a\uff0c\u8fd9\u79cd\u65b0\u65b9\u6cd5\u5c06\u6709\u52a9\u4e8e\u8bc6\u522b\u8111\u6dc0\u7c89\u6837\u86cb\u767d\u5347\u9ad8\u7684\u60a3\u8005\uff0c\u5e76\u51cf\u5c11\u5bf9\u8bca\u65ad\u6027\u6dc0\u7c89\u6837\u86cb\u767dPET\u626b\u63cf\u6216\u810a\u690e\u7a7f\u523a\u7684\u9700\u6c42\u3002 \u201d<\/p>\n
\u672c\u65b0\u95fb\u7a3f\u8ba8\u8bba\u4e86\u5f00\u53d1\u7684\u836f\u7269\u7684\u8bd5\u9a8c\u6027\u7528\u9014\uff0c\u5e76\u4e0d\u65e8\u5728\u4f20\u8fbe\u5173\u4e8e\u6709\u6548\u6027\u6216\u5b89\u5168\u6027\u7684\u7ed3\u8bba\u3002\u65e0\u6cd5\u4fdd\u8bc1\u6b64\u7c7b\u8bd5\u9a8c\u6027\u836f\u7269\u5c06\u6210\u529f\u5b8c\u6210\u4e34\u5e8a\u5f00\u53d1\u6216\u83b7\u5f97\u536b\u751f\u4e3b\u7ba1\u90e8\u95e8\u6279\u51c6\u3002<\/p>\n
<\/p>\n
[\u7f16\u8005\u6ce8]<\/strong><\/p>\n 1.<\/strong>\u5173\u4e8e<\/strong>Lecanemab<\/strong>\uff08<\/strong>BAN2401<\/strong>\uff09<\/strong><\/p>\n Lecanemab\u662f\u4e00\u79cd\u62df\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff08AD\uff09\u7684\u8bd5\u9a8c\u6027\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u662f\u536b\u6750\u548cBioArctic\u7684\u5408\u4f5c\u7814\u53d1\u7ed3\u679c\u3002Lecanemab\u53ef\u9009\u62e9\u6027\u7ed3\u5408\u4e2d\u548c\u5e76\u6d88\u9664\u53ef\u6eb6\u6027\u3001\u6bd2\u6027\u03b2\uff08A\u03b2\uff09\u6dc0\u7c89\u6837\u86cb\u767d\u805a\u96c6\u4f53\uff08\u539f\u7ea4\u7ef4\uff09\uff0c\u8fd9\u4e9b\u805a\u96c6\u4f53\u88ab\u8ba4\u4e3a\u52a0\u901f\u4e86AD\u7684\u795e\u7ecf\u7cfb\u7edf\u53d8\u6027\u8fdb\u7a0b\u3002\u56e0\u6b64\uff0cLecanemab\u53ef\u80fd\u5bf9\u75be\u75c5\u75c5\u7406\u673a\u5236\u4ea7\u751f\u5f71\u54cd\uff0c\u5e76\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u3002\u5c31\u6cbb\u759718\u4e2a\u6708\u65f6\u9884\u5148\u6307\u5b9a\u7684\u5206\u6790\u7ed3\u679c\u800c\u8a00\uff0c\u7814\u7a76201\u8868\u660e\uff0c\u65e9\u671fAD\u53d7\u8bd5\u8005\u7684\u8111A\u03b2\u84c4\u79ef\u51cf\u5c11\uff08P<0.0001\uff09\uff0cADCOMS*\u6d4b\u5f97\u7684\u75be\u75c5\u8fdb\u5c55\u51cf\u7f13\uff08P<0.05\uff09\u3002\u8be5\u7814\u7a76\u5728\u6cbb\u759712\u4e2a\u6708\u65f6\u672a\u8fbe\u5230\u4e3b\u8981\u7ed3\u5c40\u6307\u6807**\u3002\u5728\u6838\u5fc3\u9636\u6bb5\u548c\u6cbb\u7597\u95f4\u9694\u671f\uff08\u5e73\u574724\u4e2a\u6708\uff09\u540e\u542f\u52a8\u7814\u7a76201\u7684\u5f00\u653e\u671f\u5ef6\u7eed\u8bd5\u9a8c\uff0c\u4ee5\u8bc4\u4ef7\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u8be5\u9636\u6bb5\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u4e2d\u3002<\/p>\n \u6839\u636e2007\u5e7412\u6708\u4e0eBioArctic\u7b7e\u8ba2\u7684\u534f\u8bae\uff0c\u536b\u6750\u83b7\u5f97\u4e86Lecanemab\u7528\u4e8e\u6cbb\u7597AD\u7684\u5168\u7403\u7814\u7a76\u3001\u5f00\u53d1\u3001\u751f\u4ea7\u548c\u4e0a\u5e02\u6743\u5229\u30022014\u5e743\u6708\uff0c\u536b\u6750\u548c\u6e24\u5065\u7b7e\u8ba2\u4e86Lecanemab\u7684\u8054\u5408\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u534f\u8bae\uff0c\u53cc\u65b9\u4e8e2017\u5e7410\u6708\u4fee\u8ba2\u4e86\u8be5\u534f\u8bae\u3002\u76ee\u524d\uff0c\u6839\u636eII\u671f\u4e34\u5e8a\u7814\u7a76\uff08\u7814\u7a76201\uff09\u7684\u7ed3\u679c\uff0c\u6b63\u5728\u8fdb\u884c\u75c7\u72b6\u6027\u65e9\u671fAD\u7684Lecanemab\u5173\u952e\u6027III\u671f\u4e34\u5e8a\u7814\u7a76\uff08Clarity-AD\uff092020\u5e747\u6708\uff0c\u9488\u5bf9\u4e34\u5e8a\u524dAD\u4e2a\u4f53\uff08\u8fd9\u4e9b\u60a3\u8005\u4e34\u5e8a\u8868\u73b0\u6b63\u5e38\uff0c\u4f46\u5927\u8111\u4e2d\u6dc0\u7c89\u6837\u86cb\u767d\u6c34\u5e73\u4e3a\u4e2d\u7b49\u6216\u504f\u9ad8\uff09\u542f\u52a8\u4e86III\u671f\u4e34\u5e8a\u7814\u7a76\uff08AHEAD 3-45\uff09\u3002\u4ee5\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u5206\u90e8\u56fd\u7acb\u8001\u9f84\u5316\u7814\u7a76\u6240\u8d44\u52a9\u7684\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u8054\u76df\uff08\u8be5\u8054\u76df\u4e3a\u7f8e\u56fd\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u76f8\u5173\u75f4\u5446\u75c7\u7684\u5b66\u672f\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u57fa\u7840\u8bbe\u65bd\uff09\u548c\u536b\u6750\u4e0e\u6e24\u5065\u4e4b\u95f4\u7684\u516c\u79c1\u5408\u4f5c\u6a21\u5f0f\u8fdb\u884cAHEAD 3-45\u7814\u7a76\u3002<\/p>\n *\u7531\u536b\u6750\u5f00\u53d1\u7684ADCOMS\uff08AD\u7efc\u5408\u8bc4\u5206\uff09\u7ed3\u5408\u4e86ADAS-Cog\uff08\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u8bc4\u4f30\u91cf\u8868-\u8ba4\u77e5\u5206\u91cf\u8868\uff09\u3001CDR\uff08\u4e34\u5e8a\u75f4\u5446\u8bc4\u5b9a\u91cf\u8868\uff09\u548cMMSE\uff08\u7b80\u6613\u7cbe\u795e\u72b6\u6001\u68c0\u67e5\u8868\uff09\u91cf\u8868\u7684\u9879\u76ee\uff0c\u4ee5\u4fbf\u7075\u654f\u5730\u68c0\u6d4b\u65e9\u671fAD\u75c7\u72b6\u7684\u4e34\u5e8a\u529f\u80fd\u53d8\u5316\u548c\u8bb0\u5fc6\u53d8\u5316\u3002<\/p>\n **\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cADCOMS\u6d4b\u5f97\u7684\u6cbb\u759712\u4e2a\u6708\u65f6\u4e34\u5e8a\u8870\u9000\u8f83\u57fa\u7ebf\u51cf\u7f13\u226525%\u7684\u4f30\u8ba1\u6982\u7387\u226580%\u3002<\/p>\n <\/p>\n 2.<\/strong>\u536b\u6750\u4e0e\u6e24\u5065\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u65b9\u9762\u7684\u5408\u4f5c<\/strong><\/p>\n \u536b\u6750\u548c\u6e24\u5065\u5728AD\u6cbb\u7597\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u65b9\u9762\u8fdb\u884c\u4e86\u5408\u4f5c\u3002\u536b\u6750\u662fLecanemab\u8054\u5408\u5f00\u53d1\u7684\u7275\u5934\u4eba\u3002<\/p>\n <\/p>\n 3.<\/strong>\u536b\u6750\u4e0e<\/strong>BioArctic<\/strong>\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u65b9\u9762\u7684\u5408\u4f5c<\/strong><\/p>\n \u81ea2005\u5e74\u4ee5\u6765\uff0cBioArctic\u4e0e\u536b\u6750\u5c31AD\u6cbb\u7597\u836f\u7269\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u8fdb\u884c\u4e86\u957f\u671f\u5408\u4f5c\u30022007\u5e7412\u6708\u7b7e\u7f72\u4e86Lecanemab\u6297\u4f53\u7684\u5546\u4e1a\u5316\u534f\u8bae\uff0c2015\u5e745\u6708\u7b7e\u7f72\u4e86AD\u6297\u4f53Lecanemab\u5907\u4efd\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u534f\u8bae\u3002\u536b\u6750\u8d1f\u8d23AD\u4ea7\u54c1\u7684\u4e34\u5e8a\u5f00\u53d1\u3001\u4e0a\u5e02\u7533\u8bf7\u548c\u5546\u4e1a\u5316\u3002BioArctic\u4e0d\u627f\u62c5\u7528\u4e8eAD\u7684lecanemab\u7684\u5f00\u53d1\u6210\u672c\u3002<\/p>\n <\/p>\n 4.<\/strong>\u5173\u4e8e\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u4e34\u5e8a\u8bd5\u9a8c\u8054\u76df\uff08<\/strong>ACTC<\/strong>\uff09\u548c<\/strong>AHEAD 3-45<\/strong>\u8bd5\u9a8c<\/strong><\/p>\n \u7531\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u56fd\u7acb\u8001\u9f84\u5316\u7814\u7a76\u6240\uff08\u62e8\u6b3e\u7f16\u53f7U24AG057437\uff09\u8d44\u52a9\u7684ACTC\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u76f8\u5173\u75f4\u5446\u7684\u5b66\u672f\u4e34\u5e8a\u8bd5\u9a8c\u63d0\u4f9b\u57fa\u7840\u8bbe\u65bd\u3002\u8be5\u8054\u76df\u7531\u5357\u52a0\u5dde\u5927\u5b66\u3001\u54c8\u4f5b\u5927\u5b66\u548c\u6885\u5965\u8bca\u6240\u7ec4\u6210\uff0c\u5305\u62ec\u652f\u6301\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u3001\u751f\u7269\u7edf\u8ba1\u3001\u4fe1\u606f\u5b66\u3001\u533b\u7597\u5b89\u5168\u3001\u76d1\u7ba1\u76d1\u7763\u3001\u62db\u52df\u3001\u4e34\u5e8a\u8fd0\u8425\u3001\u6570\u636e\u7ba1\u7406\u3001\u7814\u7a76\u4e2d\u5fc3\u76d1\u6d4b\u3001\u4e00\u4e2a\u751f\u7269\u6807\u5fd7\u7269\u5b9e\u9a8c\u5ba4\u548c\u5b58\u50a8\u5e93\u4ee5\u53ca\u795e\u7ecf\u5f71\u50cf\u5b66\u9886\u57df\u7684\u4e13\u5bb6\u5355\u4f4d\u3002ACTC\u5305\u62ec\u5168\u7f8e35\u5bb6\u4e3b\u8981\u4e34\u5e8a\u7814\u7a76\u4e2d\u5fc3\u3002<\/p>\n AHEAD 3-45\u662f\u4e00\u9879\u7531ACTC\u3001\u536b\u6750\u548c\u6e24\u5065\u4ee5\u516c\u79c1\u5408\u4f5c\u6a21\u5f0f\u5f00\u5c55\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n <\/p>\n 5.<\/strong>\u5173\u4e8e\u536b\u6750\u682a\u5f0f\u4f1a\u793e<\/strong><\/p>\n \u536b\u6750\u682a\u5f0f\u4f1a\u793e\u662f\u4e00\u5bb6\u603b\u90e8\u4f4d\u4e8e\u65e5\u672c\u7684\u9886\u5148\u5168\u7403\u5236\u836f\u516c\u53f8\u3002\u536b\u6750\u682a\u5f0f\u4f1a\u793e\u7684\u4f01\u4e1a\u7406\u5ff5\u57fa\u4e8e\u5173\u5fc3\u4eba\u7c7b\u5065\u5eb7\uff08<\/em>hhc<\/em>\uff09<\/em>\u7406\u5ff5\uff0c\u5373\u5c06\u60a3\u8005\u53ca\u5bb6\u5c5e\u7684\u5229\u76ca\u653e\u5728\u9996\u4f4d\uff0c\u4e3a\u63d0\u5347\u5176\u798f\u7949\u505a\u51fa\u8d21\u732e\u3002\u516c\u53f8\u51ed\u501f\u7814\u53d1\u673a\u6784\u3001\u751f\u4ea7\u57fa\u5730\u548c\u8425\u9500\u5b50\u516c\u53f8\u7684\u5168\u7403\u7f51\u7edc\uff0c\u81f4\u529b\u4e8e\u901a\u8fc7\u9488\u5bf9\u533b\u7597\u9700\u6c42\u672a\u5f97\u5230\u5145\u5206\u6ee1\u8db3\u7684\u9776\u75c5\u7076\u63d0\u4f9b\u521b\u65b0\u4ea7\u54c1\uff0c\u5c24\u5176\u4fa7\u91cd\u4e8e\u795e\u7ecf\u5b66\u548c\u80bf\u7624\u5b66\u6218\u7565\u9886\u57df\uff0c\u5b9e\u73b0\u516c\u53f8\u7684hhc<\/em>\u7406\u5ff5\u3002<\/p>\n \u536b\u6750\u8ba1\u5212\u5229\u7528\u4ece\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u6cbb\u7597\u836f\u7269\u7814\u53d1\u548c\u4e0a\u5e02\u4e2d\u83b7\u5f97\u7684\u7ecf\u9a8c\uff0c\u5efa\u7acb\u201c\u536b\u6750\u75f4\u5446\u5e73\u53f0\u201d\u3002\u536b\u6750\u8ba1\u5212\u901a\u8fc7\u8be5\u5e73\u53f0\u6784\u5efa\u201c\u75f4\u5446\u751f\u6001\u7cfb\u7edf\u201d\uff0c\u4e0e\u533b\u7597\u673a\u6784\u3001\u8bca\u65ad\u5f00\u53d1\u516c\u53f8\u3001\u7814\u7a76\u7ec4\u7ec7\u548c\u751f\u7269\u98ce\u9669\u6295\u8d44\u516c\u53f8\u7b49\u5408\u4f5c\u4f19\u4f34\u4ee5\u53ca\u79c1\u4eba\u4fdd\u9669\u673a\u6784\u3001\u91d1\u878d\u4e1a\u3001\u5065\u8eab\u4ff1\u4e50\u90e8\u3001\u6c7d\u8f66\u5236\u9020\u5546\u3001\u96f6\u552e\u5546\u548c\u62a4\u7406\u673a\u6784\u7b49\u5408\u4f5c\u4f19\u4f34\u5408\u4f5c\uff0c\u4e3a\u75f4\u5446\u60a3\u8005\u53ca\u5176\u5bb6\u5ead\u5e26\u6765\u65b0\u7684\u798f\u7949\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u536b\u6750\u682a\u5f0f\u4f1a\u793e\u7684\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eehttps:\/\/www.eisai.com<\/u>\u3002<\/p>\n <\/p>\n 6.<\/strong>\u5173\u4e8e\u536b\u6750\u7f8e\u56fd<\/strong><\/p>\n \u5728\u536b\u6750\u7f8e\u56fd\uff0c\u5173\u5fc3\u4eba\u7c7b\u5065\u5eb7\uff08<\/em>hhc<\/em>\uff09<\/em>\u662f\u6211\u4eec\u7684\u76ee\u6807\u3002\u6211\u4eec\u5c06\u60a3\u8005\u53ca\u5bb6\u5c5e\u7684\u5229\u76ca\u653e\u5728\u9996\u4f4d\uff0c\u4e3a\u63d0\u5347\u5176\u798f\u7949\u505a\u51fa\u8d21\u732e\u3002\u4f5c\u4e3a\u603b\u90e8\u4f4d\u4e8e\u4e1c\u4eac\u7684\u536b\u6750\u682a\u5f0f\u4f1a\u793e\u7684\u7f8e\u56fd\u5b50\u516c\u53f8\uff0c\u6211\u4eec\u5173\u7231\u60a3\u8005\uff0c\u8fd9\u9a71\u4f7f\u6211\u4eec\u52aa\u529b\u53d1\u73b0\u548c\u5f00\u53d1\u521b\u65b0\u7597\u6cd5\u4ee5\u5e2e\u52a9\u89e3\u51b3\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u3002\u536b\u6750\u662f\u4e00\u5bb6\u5168\u9762\u6574\u5408\u7684\u5236\u836f\u4f01\u4e1a\uff0c\u4e1a\u52a1\u6d89\u53ca\u80bf\u7624\u5b66\u548c\u795e\u7ecf\u75c5\u5b66\uff08\u75f4\u5446\u76f8\u5173\u75be\u75c5\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff09\u8fd9\u4e24\u5927\u5168\u7403\u4e1a\u52a1\u677f\u5757\u3002\u6211\u4eec\u7684\u7f8e\u56fd\u603b\u90e8\u3001\u5546\u4e1a\u548c\u4e34\u5e8a\u5f00\u53d1\u7ec4\u7ec7\u4f4d\u4e8e\u65b0\u6cfd\u897f\u5dde\uff1b\u63a2\u7d22\u5b9e\u9a8c\u5ba4\u4f4d\u4e8e\u9a6c\u8428\u8bf8\u585e\u5dde\u548c\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5dde\uff1b\u5168\u7403\u9700\u6c42\u94fe\u7ec4\u7ec7\u4f4d\u4e8e\u9a6c\u91cc\u5170\u5dde\u548c\u5317\u5361\u7f57\u6765\u7eb3\u5dde\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u536b\u6750\u516c\u53f8\u7684\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95eewww.eisai.com\/US<\/u> \uff0c\u5e76\u5173\u6ce8\u6211\u4eec\u7684Twitter<\/u>\u548cLinkedIn<\/u>\u8d26\u53f7\u3002<\/p>\n <\/p>\n 7.<\/strong>\u5173\u4e8e\u6e24\u5065<\/strong><\/p>\n \u4f5c\u4e3a\u795e\u7ecf\u79d1\u5b66\u7684\u5148\u950b\uff0c\u6e24\u5065\u4e3a\u5168\u7403\u7f79\u60a3\u4e25\u91cd\u795e\u7ecf\u75be\u75c5\u7684\u60a3\u8005\u63a2\u5bfb\u3001\u7814\u53d1\u548c\u63d0\u4f9b\u521b\u65b0\u7597\u6cd5\u3002\u6e24\u5065\u662fCharles Weissmann\u3001Heinz Schaller\u3001Sir Kenneth Murray\u4e0e\u8bfa\u8d1d\u5c14\u5956\u83b7\u5f97\u8005Walter Gilbert\u548cPhillip Sharp\u643a\u624b\u57281978\u5e74\u6210\u7acb\u7684\u5168\u7403\u9996\u6279\u751f\u7269\u79d1\u6280\u516c\u53f8\u4e4b\u4e00\u3002\u5982\u4eca\uff0c\u6e24\u5065\u62e5\u6709\u6cbb\u7597\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u9886\u5148\u836f\u7269\u7ec4\u5408\uff0c\u63a8\u51fa\u4e86\u9996\u4e2a\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7\u7684\u836f\u7269\uff0c\u5e76\u6b63\u5728\u63d0\u4f9b\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u83b7\u6279\u7528\u4e8e\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u660e\u786e\u75c5\u7406\u5b66\u7279\u5f81\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n \u6e24\u5065\u8fd8\u5728\u8fdb\u884c\u751f\u7269\u7c7b\u4f3c\u836f\u5546\u4e1a\u5316\uff0c\u5e76\u81f4\u529b\u4e8e\u63a8\u8fdb\u795e\u7ecf\u79d1\u5b66\u9886\u57df\u884c\u4e1a\u7684\u6700\u591a\u6837\u5316\u6e20\u9053\uff0c\u8fd9\u5c06\u6539\u53d8\u5177\u6709\u9ad8\u5ea6\u672a\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u7684\u82e5\u5e72\u9886\u57df\u60a3\u8005\u7684\u6807\u51c6\u6cbb\u7597\u3002<\/p>\n 2020\u5e74\uff0c\u6e24\u5065\u53d1\u8d77\u4e86\u4e00\u9879\u4e3a\u671f20\u5e74\u3001\u8017\u8d442.5\u4ebf\u7f8e\u5143\u7684\u5927\u80c6\u5021\u8bae\uff0c\u65e8\u5728\u89e3\u51b3\u6c14\u5019\u3001\u5065\u5eb7\u548c\u516c\u5e73\u7b49\u5bc6\u5207\u76f8\u5173\u7684\u95ee\u9898\u3002Healthy Climate, Healthy 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