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style=\"text-align: left\"><sup>1 <\/sup>Kansal AR, Tafazzoli A, Ishak KJ, Krotneva S. Alzheimer&#8217;s disease Archimedes condition-event simulator: Development and validation.<em>Alzheimers Dement <\/em>(NY).2018;4:76-88.Published 2018 Feb 16. doi:10.1016\/j.trci.2018.01.001.<\/p>\n<p style=\"text-align: left\"><sup>2<\/sup> Tafazzoli and Kansal. Disease simulation in drug development, External validation confirms benefit in decision making.The Evidence Forum.2018.<\/p>\n<p style=\"text-align: left\"><u>https:\/\/www.evidera.com\/wp-content\/uploads\/2018\/10\/07-Disease-Simulation-in-Drug-Development_Fall2018.pdf<\/u><\/p>\n<p style=\"text-align: left\"><sup>3<\/sup> Tafazzoli A, Weng J, Sutton K, et al. Validating simulated cognition trajectories based on ADNI against 436 trajectories from the National Alzheimer&#8217;s Coordinating Center (NACC) dataset.11th edition of Clinical Trials on 437 Alzheimer&#8217;s Disease (CTAD); Barcelona, Spain: 2018.<\/p>\n<p style=\"text-align: left\"><sup>4 <\/sup>Tahami Monfared AA, Tafazzoli A, Ye W, Chavan A, Zhang Q. Long-Term Health Outcomes of Lecanemab in Patients with Early Alzheimer\u2019s Disease Using Simulation Modeling. <em>Neurol Ther <\/em>11, 863\u2013880 (2022). https:\/\/link.springer.com\/article\/10.1007\/s40120-022-00350-y.<\/p>\n<p style=\"text-align: left\"><sup>5<\/sup> ICER Value Framework 2020-2023. 2022.<u>ICER_2020_2023_VAF_02032022.pdf<\/u><\/p>\n<p style=\"text-align: left\"><sup>6 <\/sup>Alzheimer&#8217;s Association. 2022 Alzheimer\u2019s Disease Facts and Figures 2022 Available from: alzheimers-facts-and- figures.pdf.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u5a92\u4f53\u54a8\u8be2\uff1a<\/strong><\/p>\n<p>\u516c\u5171\u5173\u7cfb\u90e8\uff0c<\/p>\n<p>\u536b\u6750\u682a\u5f0f\u4f1a\u793e<\/p>\n<p>+81-(0)3-3817-5120<\/p>\n<p>&nbsp;<\/p>\n<p>\u536b\u6750\u7f8e\u56fd<\/p>\n<p>Libby Holman<\/p>\n<p>Libby_Holman@Eisai.com<\/p>\n<p>201-753-1945<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7b2c\u4e8c\u7bc7\u4f7f\u7528\u6a21\u62df\u6a21\u578b\u7814\u7a76Lecanemab\u6cbb\u7597\u65e9\u671f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u7684\u6f5c\u5728\u4ef7\u503c\u7684\u6587\u7ae0<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-6320","post","type-post","status-publish","format-standard","hentry","category-news-zh"],"_links":{"self":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/6320"}],"collection":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/comments?post=6320"}],"version-history":[{"count":5,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/6320\/revisions"}],"predecessor-version":[{"id":6322,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/posts\/6320\/revisions\/6322"}],"wp:attachment":[{"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/media?parent=6320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/categories?post=6320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.eisai.com.cn\/wp-json\/wp\/v2\/tags?post=6320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}